DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5890 and Kcnip2

DIOPT Version :9

Sequence 1:	NP_001356889.1	Gene:	CG5890 / 43126	FlyBaseID:	FBgn0039380	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_064479.2	Gene:	Kcnip2 / 56817	RGDID:	70887	Length:	270	Species:	Rattus norvegicus

Alignment Length:	179	Identity:	87/179 - (48%)
Similarity:	134/179 - (74%)	Gaps:	0/179 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PVALEDLCRQTKFTKQEIRVMYRGFKTECPEGVVHEDCFKDIYAKFFPHGNSSLYAHYVFKAFDV 90
            |..||.|..|||||::|::|:|||||.|||.|:|:|:.||.||::|||.|:||.||.::|.|||.
  Rat    90 PEGLEQLQEQTKFTRRELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSNYATFLFNAFDT 154

  Fly    91 NCNGAISFRDLLVTLSTLLRGSVYERLRWTFKLYDLNGDGRISRGELSEIILAIHELMGRRPHQP 155
            |.:|::||.|.:..||.:|||::.:||.|.|.|||||.||.|::.|:.:|:.:|:::||:..:..
  Rat   155 NHDGSVSFEDFVAGLSVILRGTIDDRLSWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPA 219

  Fly   156 EDDRKARDQVDRVFRKLDLNQDGIITIEEFLEACLKDDLVTRSLQMFDN 204
            ..:...|:.|:..|:|:|.|:||::|||||:|:|.:|:.:.||:|:|||
  Rat   220 LREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQQDENIMRSMQLFDN 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5890	NP_001356889.1	FRQ1	29..192	CDD:227455	79/162 (49%)
Kcnip2	NP_064479.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
		FRQ1	93..259	CDD:227455	80/165 (48%)
		Interaction with KCND2. /evidence=ECO:0000250\|UniProtKB:Q8R426	257..270		6/12 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337001
Domainoid	1	1.000	96	1.000	Domainoid score	I7128
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3579
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606780at33208
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	1	1.000	-	-		otm44648
orthoMCL	1	0.900	-	-		OOG6_101448
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.900