DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5890 and efcab1

DIOPT Version :9

Sequence 1:	NP_001356889.1	Gene:	CG5890 / 43126	FlyBaseID:	FBgn0039380	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_001038325.1	Gene:	efcab1 / 558421	ZFINID:	ZDB-GENE-040914-40	Length:	216	Species:	Danio rerio

Alignment Length:	184	Identity:	53/184 - (28%)
Similarity:	95/184 - (51%)	Gaps:	13/184 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 EDLCRQTK-FTKQEIRVMYRGFKTECPEGVVHEDCFKDIYAKF---FPHG---NSSLYAHYVFKA 87
            |.||||.| |.|.|...:.|.|.:...|....:.......|||   ..|.   ...:....|.:.
Zfish    17 ETLCRQVKHFNKTETECLIRLFNSLLGEQAERKTTIGVDRAKFRNILHHTFGMTDDMMTDRVCRV 81

  Fly    88 FDVNCNGAISFRDLLVTLSTLLRGSVYERLRWTFKLYDLNGDGRISRGELSEIILAIHELMGRRP 152
            .|.:.:|.:|.::.:..||..|||::.|::::.|::|||||||.|||.|:.::   :.:.:.|:|
Zfish    82 IDKDNDGYLSVKEWVEALSVFLRGTLDEKMKYCFEVYDLNGDGYISREEMFQM---LKDSLIRQP 143

  Fly   153 HQPEDDRKARDQVDRVFRKLDLNQDGIITIEEFLEACLKDDLVTRSLQMFDNDL 206
            .:.:.|...:|.|:...:|:|.:.||.::..:|.:..:.::|:   |:.|.|.|
Zfish   144 TEEDPDEGIKDIVEIALKKMDYDHDGRVSYADFEKTVMDENLL---LEAFGNCL 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5890	NP_001356889.1	FRQ1	29..192	CDD:227455	48/168 (29%)
efcab1	NP_001038325.1	EFh	80..136	CDD:238008	21/58 (36%)
		EF-hand_7	80..135	CDD:290234	21/57 (37%)
		EFh	110..176	CDD:238008	21/68 (31%)
		EF-hand_7	111..178	CDD:290234	22/69 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576131
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840