DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5890 and Duox2

DIOPT Version :9

Sequence 1:	NP_001356889.1	Gene:	CG5890 / 43126	FlyBaseID:	FBgn0039380	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_001349684.1	Gene:	Duox2 / 214593	MGIID:	3036280	Length:	1545	Species:	Mus musculus

Alignment Length:	128	Identity:	33/128 - (25%)
Similarity:	61/128 - (47%)	Gaps:	14/128 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 LYAHYVFKAFDVNCNGAISFRDLLVTLSTLLRGSVYERLRWTFKLYDLNGDGRISRGELSEIILA 143
            ::...:|...|.:.||.||||:.|..|...::||..::.|..|.:|||:|:|.:|:.|...::.:
Mouse   822 MFVESMFSLADKDGNGYISFREFLDILVVFMKGSSEDKSRLMFTMYDLDGNGFLSKDEFFTMMRS 886

  Fly   144 IHELMGRRPHQPEDDRKARDQVDRVFRKLDLNQDGIITIEEFLEACLKDDLVTRSLQMFDNDL 206
            ..|:......:.:    ..:.|:.:||:........:|.|:| ...|:|         .|:||
Mouse   887 FIEISNNCLSKAQ----LAEVVESMFRESGFQDKEELTWEDF-HFMLRD---------HDSDL 935

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5890	NP_001356889.1	FRQ1	29..192	CDD:227455	29/112 (26%)
Duox2	NP_001349684.1	dual_peroxidase_like	38..594	CDD:188652
		EFh	824..885	CDD:238008	21/60 (35%)
		EFh	861..919	CDD:238008	13/61 (21%)
		Ferric_reduct	1085..1229	CDD:366815
		NOX_Duox_like_FAD_NADP	1271..1545	CDD:99783
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910