DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5890 and DUOX

DIOPT Version :9

Sequence 1:	NP_001356889.1	Gene:	CG5890 / 43126	FlyBaseID:	FBgn0039380	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	XP_319115.4	Gene:	DUOX / 1279399	VectorBaseID:	AGAP009978	Length:	1475	Species:	Anopheles gambiae

Alignment Length:	128	Identity:	32/128 - (25%)
Similarity:	61/128 - (47%)	Gaps:	3/128 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 VVHEDCFKDIYAKFFPHGNSSLYAHYVFKAFDVNCNGAISFRDLLVTLSTLLRGSVYERLRWTFK 122
            |:.....|..:|.........::...:|...|.:.:|.|||::.|.|:....||...::||..|.
Mosquito   775 VMRTSLSKSEFAAALGMKQDDMFVRKMFNIVDKDKDGRISFQEFLETVVLFSRGKTDDKLRIIFD 839

  Fly   123 LYDLNGDGRISRGELSEIILAIHELMGRRPHQPEDDRKARDQVDRVFRKLDLNQDGIITIEEF 185
            :.|.:.:|.|.:|||||::.::.|:...   ....|.:..:.:|.:|:.:.|.....:|.|:|
Mosquito   840 MCDNDRNGVIDKGELSEMMRSLVEIART---TSVTDEQVNELIDGMFQDVGLEHKNHLTYEDF 899

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5890	NP_001356889.1	FRQ1	29..192	CDD:227455	32/128 (25%)
DUOX	XP_319115.4	An_peroxidase	7..518	CDD:281139
		dual_peroxidase_like	9..562	CDD:188652
		EFh	766..823	CDD:298682	11/47 (23%)
		EFh	798..859	CDD:238008	21/60 (35%)
		EF-hand_7	798..858	CDD:290234	21/59 (36%)
		EFh	833..904	CDD:238008	19/70 (27%)
		EF-hand_7	837..903	CDD:290234	17/66 (26%)
		Ferric_reduct	1022..1155	CDD:280043
		NOX_Duox_like_FAD_NADP	1203..1380	CDD:99783
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910