DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5890 and CIB1

DIOPT Version :9

Sequence 1:	NP_001356889.1	Gene:	CG5890 / 43126	FlyBaseID:	FBgn0039380	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	XP_006720438.1	Gene:	CIB1 / 10519	HGNCID:	16920	Length:	264	Species:	Homo sapiens

Alignment Length:	193	Identity:	44/193 - (22%)
Similarity:	90/193 - (46%)	Gaps:	31/193 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 TRVPKPIPVALEDLCRQTKFTKQEIRVMYRGFKTECPE-------GVVHEDCFKDIYAKFFPHGN 76
            :|:.|.:....:||   |..|||||.:.:|.|....|:       .:..:..|:.|.:  .|...
Human     6 SRLSKELLAEYQDL---TFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS--LPELK 65

  Fly    77 SSLYAHYVFKAFDVN-CNGAISFRDLLVTLSTLLRGSVYE-RLRWTFKLYDLNGDGRISRGELSE 139
            ::.:...:.:.|..: ...::||.|.|..||.....:..: :..:.|:::|.:.||.::|.:||.
Human    66 ANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSR 130

  Fly   140 IILAIHELMGRRPHQPEDDR----KARDQVDRVFRKLDLNQDGIITIEEFLEACLKDDLVTRS 198
            :   ::.|.|    :.||.|    :.:..:|.:..:.|:::||.|.:.||      ..:::||
Human   131 L---VNCLTG----EGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEF------QHVISRS 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5890	NP_001356889.1	FRQ1	29..192	CDD:227455	40/175 (23%)
CIB1	XP_006720438.1	EF-hand_8	82..132	CDD:290545	13/52 (25%)
		EF-hand_7	109..177	CDD:290234	19/80 (24%)
		EFh	111..178	CDD:238008	19/79 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910