DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5890 and klhl17

DIOPT Version :9

Sequence 1:	NP_001356889.1	Gene:	CG5890 / 43126	FlyBaseID:	FBgn0039380	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	XP_004916201.1	Gene:	klhl17 / 100491332	XenbaseID:	XB-GENE-977875	Length:	627	Species:	Xenopus tropicalis

Alignment Length:	156	Identity:	36/156 - (23%)
Similarity:	55/156 - (35%)	Gaps:	46/156 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PVALEDLCRQTKFTKQEIRVMYRGFKTECPEGV------VHEDCFKDIYAKFFPHGNSSLYAHYV 84
            |.|||.|. |..:| .||.|.....:|..|...      |.:.|.|.:.::..|.
Frog   125 PQALEQLV-QYAYT-AEIVVGEGNVQTLLPAASLLQLNGVRDACCKFLLSQLDPS---------- 177

  Fly    85 FKAFDVNCNGAISFRDLLVTLSTLLRGSVYERLRWTF---------------KLYDLNGDGRISR 134
                  ||.|...|.| ..:.|.||: |.::.:...|               ::.||.....::.
Frog   178 ------NCLGIRGFAD-THSCSDLLK-SAHKYVLQHFVEVSKTEEFMLLPLKQVLDLISSDSLNV 234

  Fly   135 GELSEIILAI-----HELMGRRPHQP 155
            ....|:..|:     |::.|||.|.|
Frog   235 PSEEEVYRAVLNWVKHDVDGRRQHVP 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5890	NP_001356889.1	FRQ1	29..192	CDD:227455	34/153 (22%)
klhl17	XP_004916201.1	BTB_POZ_KLHL17_actinfilin	38..176	CDD:349555	15/52 (29%)
		PHA03098	77..543	CDD:222983	36/156 (23%)
		KELCH repeat	321..360	CDD:276965
		KELCH repeat	364..407	CDD:276965
		KELCH repeat	411..454	CDD:276965
		KELCH repeat	458..502	CDD:276965
		KELCH repeat	505..549	CDD:276965
		KELCH repeat	552..597	CDD:276965
		Kelch	564..608	CDD:128874
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000