DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5890 and kcnip2

DIOPT Version :9

Sequence 1:	NP_001356889.1	Gene:	CG5890 / 43126	FlyBaseID:	FBgn0039380	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	XP_003201187.1	Gene:	kcnip2 / 100003947	ZFINID:	ZDB-GENE-081031-91	Length:	253	Species:	Danio rerio

Alignment Length:	179	Identity:	88/179 - (49%)
Similarity:	132/179 - (73%)	Gaps:	0/179 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PVALEDLCRQTKFTKQEIRVMYRGFKTECPEGVVHEDCFKDIYAKFFPHGNSSLYAHYVFKAFDV 90
            |.:|:.|...|||||.|::::||.||.:||.|||:|:.|:.||:.|||||:||.|||::|:|||.
Zfish    73 PDSLDKLMELTKFTKTELQILYRSFKNDCPTGVVNEETFQLIYSHFFPHGDSSAYAHFLFEAFDR 137

  Fly    91 NCNGAISFRDLLVTLSTLLRGSVYERLRWTFKLYDLNGDGRISRGELSEIILAIHELMGRRPHQP 155
            ..|||::|.|.:|.||.:|||:|.:||.|.|.|||||.||.|::.|:::|:.:|:::||:.....
Zfish   138 RKNGAVNFEDFVVGLSIILRGTVTDRLSWAFSLYDLNKDGCITKEEMNDIMKSIYDMMGKNTCPC 202

  Fly   156 EDDRKARDQVDRVFRKLDLNQDGIITIEEFLEACLKDDLVTRSLQMFDN 204
            .:|...|:.|:..|:|:|.|.||:||:|||||:|.||:.:..|:||.|:
Zfish   203 MNDSAPREHVESFFQKMDRNNDGVITMEEFLESCQKDEAIMESMQMLDH 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5890	NP_001356889.1	FRQ1	29..192	CDD:227455	81/162 (50%)
kcnip2	XP_003201187.1	FRQ1	72..242	CDD:227455	84/168 (50%)
		EFh	127..189	CDD:238008	33/61 (54%)
		EFh	163..234	CDD:238008	31/70 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576140
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3687
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606780at33208
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	1	1.000	-	-		otm24851
orthoMCL	1	0.900	-	-		OOG6_101448
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.900