DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5886 and PPFIBP1

DIOPT Version :9

Sequence 1:NP_651435.1 Gene:CG5886 / 43125 FlyBaseID:FBgn0039379 Length:515 Species:Drosophila melanogaster
Sequence 2:XP_016875545.1 Gene:PPFIBP1 / 8496 HGNCID:9249 Length:1036 Species:Homo sapiens


Alignment Length:486 Identity:94/486 - (19%)
Similarity:183/486 - (37%) Gaps:152/486 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 EKNVSRLTAELRVLQRQMESQ-----------QREKEQVQRDLNKSVLMRDKLQEVCREQQRI-- 101
            |.:...|..::.||..|:|:|           :..:|:|  :..:.:|.::.|.....|.|::  
Human   110 ENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKV--NATEEMLQQELLSRTSLETQKLDL 172

  Fly   102 ---IKSVKNESLLQIKVEEERRKESQTKFQSS------LNDVQKSLAKNNEENI----KLRDYNI 153
               |.::|    |::...|:.|.:.:.||:.:      :||::..:::.:.|.:    ||:....
Human   173 MAEISNLK----LKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKS 233

  Fly   154 EMTK----KLKLLAEQY--QTREQHLEKLNEQVQLEAQLHQAKLQKCQVEAAMEKEILSKENQIG 212
            .|.|    |:|:...||  |..||..|.|.:::                 |::::::..||::: 
Human   234 LMAKLSSMKIKVGQMQYEKQRMEQKWESLKDEL-----------------ASLKEQLEEKESEV- 280

  Fly   213 LEKLMQAQRAIK------DLTDREHQLKEQL---NIYTAKYDDFQQSLQKSNEVFGSYKVELEKM 268
              |.:|.:...|      ::.||:...|::|   ||...|.....:||..:||         || 
Human   281 --KRLQEKLVCKMKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANE---------EK- 333

  Fly   269 SKHTKKIE--KEALGWRQKYEKANAMVIDLATEKSLQTQHSERLQKQIQQLQKLLRA---LQLER 328
               .:|||  ::.|   .:|:|....|:....:|....::.|.|..  ..:..||.|   ..||:
Human   334 ---DRKIEDLRQCL---NRYKKMQDTVVLAQGKKGKDGEYEELLNS--SSISSLLDAQGFSDLEK 390

  Fly   329 TTLHKCLRDHEIEIPALPQLPPEPEPVNVKPVS-------AENVKMEMMSRNCAELKQTLANLQN 386
            :                    |.|.||...|..       .|.....::..:...|.....:::.
Human   391 S--------------------PSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMET 435

  Fly   387 QMKLLTTNESKTSIEEK----------------KKAEEQRQANNAKKNIRKKEKKSKAKAAAAAA 435
            ..|...|.:.:||.||.                |......|.:::..|::|:             
Human   436 SEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKE------------- 487

  Fly   436 AEAAASTTNGEANGVQESAATESKAELEAAG 466
                  |::||...:|:::...:.||....|
Human   488 ------TSDGEKETIQKTSEDRAPAESRPFG 512

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5886NP_651435.1 Taxilin 22..328 CDD:286771 69/323 (21%)
PPFIBP1XP_016875545.1 SMC_N <47..352 CDD:330553 61/283 (22%)
SAM_liprin-beta1,2_repeat1 669..732 CDD:188962
SAM_liprin-beta1,2_repeat2 743..805 CDD:188965
SAM_liprin-beta1,2_repeat3 828..899 CDD:188968
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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