DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5886 and txlna

DIOPT Version :9

Sequence 1:	NP_651435.1	Gene:	CG5886 / 43125	FlyBaseID:	FBgn0039379	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001092700.1	Gene:	txlna / 324180	ZFINID:	ZDB-GENE-030131-2900	Length:	514	Species:	Danio rerio

Alignment Length:	361	Identity:	130/361 - (36%)
Similarity:	222/361 - (61%)	Gaps:	23/361 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EKLSKAKKVAREEKQRDQKLEELVMKSLDECPSAEEKV-------KLLLQRHVDSEKNVSRLTAE 59
            :||.:.|||....|:     ..|:|::|:...:.|||:       ..||:.|.:::|       :
Zfish   121 KKLQEKKKVKGLGKE-----ITLLMQTLNTLSTPEEKLGGLCKKYAELLEEHRNAQK-------Q 173

  Fly    60 LRVLQRQMESQQREKEQVQRDLNKSVLMRDKLQEVCREQQRIIKSVKNESLLQIKVEEERRKESQ 124
            :||||::.....:||:.::.:.:|::|.|.||:.:|||.||..:::|.:.:.:.::|||:|||..
Zfish   174 MRVLQKKQTQLIQEKDHLRNEHSKAILARSKLESLCRELQRHNRTLKEDGVQRARLEEEKRKEVT 238

  Fly   125 TKFQSSLNDVQKSLAKNNEENIKLRDYNIEMTKKLKLLAEQYQTREQHLEKLNEQVQLEAQLHQA 189
            :.||.:|||:|..:.::||.|..||..|:|:..|||.|.|||:.||:|::|:.:|..|:.||..|
Zfish   239 SHFQVTLNDIQAQMEQHNERNANLRQENMELADKLKKLIEQYELREEHIDKVFKQKDLQQQLVDA 303

  Fly   190 KLQKCQVEAAMEKEILSKENQIGLEKLMQAQRAIKDLTDREHQLKEQLNIYTAKYDDFQQSLQKS 254
            ||.:.|......::...||....|::..::||..:.:..:|..||:||::||.|:::||.:|.||
Zfish   304 KLHQAQGLLKDSEDRHQKEKDFLLKEAAESQRMYELMKQQEVHLKQQLSLYTEKFEEFQNTLSKS 368

  Fly   255 NEVFGSYKVELEKMSKHTKKIEKEALGWRQKYEKANAMVIDLATEKSLQTQHSERLQKQIQQLQK 319
            ||||.::|.|:|||:|..||:|||...:|.::|.:|..::::|.||:|:.:..|.||.::|:|:|
Zfish   369 NEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTLKDKDFESLQVKVQRLEK 433

  Fly   320 LLRALQLERTTLHKCLRDH----EIEIPALPQLPPE 351
            |.||||:||..|.|.::..    |..:......|||
Zfish   434 LCRALQIERNELSKKVQSFSTGAESRLDTESGSPPE 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5886	NP_651435.1	Taxilin	22..328	CDD:286771	116/312 (37%)
txlna	NP_001092700.1	Taxilin	135..442	CDD:286771	116/318 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	223	1.000	Domainoid score	I2500
eggNOG	1	0.900	-	-		E1_KOG1850
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14062
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3417
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D532685at33208
OrthoFinder	1	1.000	-	-		FOG0001051
OrthoInspector	1	1.000	-	-		otm25282
orthoMCL	1	0.900	-	-		OOG6_105608
Panther	1	1.100	-	-	LDO	PTHR16127
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3923
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.860