DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5886 and Txlnb

DIOPT Version :9

Sequence 1:	NP_651435.1	Gene:	CG5886 / 43125	FlyBaseID:	FBgn0039379	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001129331.1	Gene:	Txlnb / 308622	RGDID:	1307979	Length:	690	Species:	Rattus norvegicus

Alignment Length:	531	Identity:	158/531 - (29%)
Similarity:	274/531 - (51%)	Gaps:	57/531 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RDQKLEE-----------LVMKSLDECPSAEEKVKLLLQRH---VDSEKNVSRLTAELRVLQRQM 67
            ::||||:           |:|::|::..:.|||:..|.:::   :|..:...:   :|::|.:|.
  Rat   132 KEQKLEKKILKGLGKEANLLMQNLNKLQAPEEKLDFLFKKYAELLDEHRTEQK---KLKLLLKQQ 193

  Fly    68 ESQQREKEQVQRDLNKSVLMRDKLQEVCREQQRIIKSVKNESLLQIKVEEERRKESQTKFQSSLN 132
            ...||||:|:|.:.|:::|.|.||:.:|||.||..|::|.|:|.:.:.|||:|||..:.|||:|.
  Rat   194 AQTQREKDQLQSEHNRAILARSKLESLCRELQRHNKTLKEETLQRAREEEEKRKEITSHFQSTLT 258

  Fly   133 DVQKSLAKNNEENIKLRDYNIEMTKKLKLLAEQYQTREQHLEKLNEQVQLEAQLHQAKLQKCQ-- 195
            |:|..:.:.:|.|:||...|.|:.:|||.:.:||:.||:||:|:.:..:|:.:|..|||::.|
  Rat   259 DIQTQIEQQSERNMKLCQENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEEAQEL 323

  Fly   196 VEAAMEKEILSKENQIGLEKLMQA---QRAIKDLTDREHQLKEQLNIYTAKYDDFQQSLQKSNEV 257
            ::.|.|:....||....|..|.||   :...|.|.::|..|:.||.:|:.::::||.:|.|||||
  Rat   324 MQEAEERHRREKEYVFILLLLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEV 388

  Fly   258 FGSYKVELEKMSKHTKKIEKEALGWRQKYEKANAMVIDLATEKSLQTQHSERLQKQIQQLQKLLR 322
            |.::|.|::..:|..||:||:...|:.::|..|..::|:..||:|:.:..|....:||:|:.|.|
  Rat   389 FATFKQEMDNTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIQRLENLCR 453

  Fly   323 ALQLERTTLHKCLRD---HEIEIPALPQLPPEPEPVNVKPVSAENVKMEMMSRNCAELKQTLANL 384
            |||.||..|:|.:||   .|.|.........|||    ..|| |:.:|::.:.|         .:
  Rat   454 ALQEERKELYKKIRDAKMSEKEDQVQHTSDEEPE----SKVS-EDKQMDVEAAN---------GV 504

  Fly   385 QNQMKLLTT---------------NESKTSIEEKKKAEEQRQANNAKKNIRKKEKKSKAKAAAAA 434
            ||.:|.|.|               .|.:.::.......:....:....::......|.:.:....
  Rat   505 QNAVKNLATAFAILHHPEFTPDQSRERQPAVNGPPGGSDLTHQHTEPAHLNHPNPSSVSGSPQPP 569

  Fly   435 AAEAAASTTNGEANGVQESAATESKAELEAAG-DASNVKNEKEQTVDIATDTQELV--GDGDAIT 496
            ....|.|....||.....:..|.::|||::.| .|.|..:.|.|..:.....|..:  ..|....
  Rat   570 VGSQAGSEGGCEAAPAPTACCTPAEAELQSQGLSAGNPPDPKPQKPEAKASGQVPLSPAQGSLAV 634

  Fly   497 AKSLVDISEVP 507
            .::..|||..|
  Rat   635 VEAKCDISPSP 645

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5886	NP_651435.1	Taxilin	22..328	CDD:286771	113/324 (35%)
Txlnb	NP_001129331.1	Taxilin	147..459	CDD:286771	112/314 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339563
Domainoid	1	1.000	222	1.000	Domainoid score	I2498
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3356
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D532685at33208
OrthoFinder	1	1.000	-	-		FOG0001051
OrthoInspector	1	1.000	-	-		otm45392
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR16127
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.000