DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5886 and TXLNA

DIOPT Version :9

Sequence 1:	NP_651435.1	Gene:	CG5886 / 43125	FlyBaseID:	FBgn0039379	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	XP_016856050.1	Gene:	TXLNA / 200081	HGNCID:	30685	Length:	579	Species:	Homo sapiens

Alignment Length:	338	Identity:	124/338 - (36%)
Similarity:	218/338 - (64%)	Gaps:	15/338 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AKKVAREEKQRDQKLEELVMKSLDECPSAEEKVKL-------LLQRHVDSEKNVSRLTAELRVLQ 64
            |....::.|:..::: .|:|::|:...:.|||:..       ||:.|.:|:|       ::::||
Human   191 ASLFCQDSKENGKEI-TLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNSQK-------QMKLLQ 247

  Fly    65 RQMESQQREKEQVQRDLNKSVLMRDKLQEVCREQQRIIKSVKNESLLQIKVEEERRKESQTKFQS 129
            ::.....:||:.::.:.:|:||.|.||:.:|||.||..:|:|.|.:.:.:.|||:|||..:.||.
Human   248 KKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQV 312

  Fly   130 SLNDVQKSLAKNNEENIKLRDYNIEMTKKLKLLAEQYQTREQHLEKLNEQVQLEAQLHQAKLQKC 194
            :|||:|..:.::||.|.|||..|:|:.::||.|.|||:.||:|::|:.:...|:.||..||||:.
Human   313 TLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQA 377

  Fly   195 QVEAAMEKEILSKENQIGLEKLMQAQRAIKDLTDREHQLKEQLNIYTAKYDDFQQSLQKSNEVFG 259
            |......:|...:|....|::.:::||..:.:..:|..||:||.:||.|:::||.:|.||:|||.
Human   378 QEMLKEAEERHQREKDFLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFT 442

  Fly   260 SYKVELEKMSKHTKKIEKEALGWRQKYEKANAMVIDLATEKSLQTQHSERLQKQIQQLQKLLRAL 324
            ::|.|:|||:|..||:|||...:|.::|.:|..::::|.||:::.:..|.||.:||:|:||.|||
Human   443 TFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEKLCRAL 507

  Fly   325 QLERTTLHKCLRD 337
            |.||..|:|.::|
Human   508 QTERNDLNKRVQD 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5886	NP_651435.1	Taxilin	22..328	CDD:286771	117/312 (38%)
TXLNA	XP_016856050.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	222	1.000	Domainoid score	I2596
eggNOG	1	0.900	-	-		E1_KOG1850
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14062
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3435
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D532685at33208
OrthoFinder	1	1.000	-	-		FOG0001051
OrthoInspector	1	1.000	-	-		otm41262
orthoMCL	1	0.900	-	-		OOG6_105608
Panther	1	1.100	-	-	LDO	PTHR16127
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3923
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.860