Protein Alignment alpha4GT2 and A4GALT

DIOPT Version :9

• Sequence 1: NP_651434.3
• Gene: alpha4GT2 / 43124
• FlyBaseID: FBgn0039378
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_001304967.1
• Gene: A4GALT / 53947
• HGNCID: 18149
• Length: 353
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 95/322 - (29%)
• Similarity: 148/322 - (45%)
• Gaps: 25/322 - (7%)

  Fly    74 QSKFKLDKVSKKIPVIPLLDVLKAKKQPSRGQNIFFHETTNFKRIEKSSVVQLTAREACAIESAA 138
            :.|.:|..:..:||...|.........|:.| ||||.||::  |...:.:..      |::||||
Human    47 KEKGQLYNLPAEIPCPTLTPPTPPSHGPTPG-NIFFLETSD--RTNPNFLFM------CSVESAA 102

  Fly   139 LHNPGLTVFVLFAGATHRPSSGDPL-----IRALHNYKNIRLRHLNLWRYAAGTPIAKWLKSGKL 198
            ..:|...|.||..|.   |.....|     |..|..:.|:::..|:|......||:|.|..:.:.
Human   103 RTHPESHVLVLMKGL---PGGNASLPRHLGISLLSCFPNVQMLPLDLRELFRDTPLADWYAAVQG 164

  Fly   199 FKSKFLFPHVSDLLRYVSLYKYGGLYLDLDVVVQQNLEKLPPNFTGAESNISVACGVMKMSPGGL 263
            ....:|.|.:||..|...::|:||:|||.|.:|.:||..| .|..|.:|...:....:...   .
Human   165 RWEPYLLPVLSDASRIALMWKFGGIYLDTDFIVLKNLRNL-TNVLGTQSRYVLNGAFLAFE---R 225

  Fly   264 GHKIATMCLRDLEANYNANKWGTNGPGVITRVVKKQCNTDNIKSVINNPKRCNGFKVFDANAFYA 328
            .|:...:|:||...:||...||..||.::|||.||.|   :|:|:..: :.|.|.......|||.
Human   226 RHEFMALCMRDFVDHYNGWIWGHQGPQLLTRVFKKWC---SIRSLAES-RACRGVTTLPPEAFYP 286

  Fly   329 ISWLQWKDFFQPNRHNVTMKRVSKSPVIHVWNKFSKGWKVKTKSNCAYTTLAKIHCPRSFAA 390
            |.|..||.:|:........:.:|.:..:|||||.|:|.:.:..|......|...:||.:..|
Human   287 IPWQDWKKYFEDINPEELPRLLSATYAVHVWNKKSQGTRFEATSRALLAQLHARYCPTTHEA 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha4GT2	NP_651434.3	Gly_transf_sug	129..241	CDD:303104	37/116 (32%)
		Gb3_synth	265..391	CDD:282437	41/126 (33%)
A4GALT	NP_001304967.1	Gly_transf_sug	94..214	CDD:327708	40/129 (31%)
		DXD motif. /evidence=ECO:0000250	192..194		1/1 (100%)
		Gb3_synth	227..349	CDD:309631	41/126 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155306
Domainoid	1	1.000	94	1.000	Domainoid score	I7483
eggNOG	1	0.900	-	-		E1_KOG1928
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9690
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4301
Isobase	1	0.950	-	0	Normalized mean entropy	S7577
OMA	1	1.010	-	-		QHG47281
OrthoDB	1	1.010	-	-		D1082380at2759
OrthoFinder	1	1.000	-	-		FOG0000423
OrthoInspector	1	1.000	-	-		mtm8452
orthoMCL	1	0.900	-	-		OOG6_104694
Panther	1	1.100	-	-	O	PTHR12042
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X281
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720