DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5024 and MYL4

DIOPT Version :9

Sequence 1:	NP_001163736.1	Gene:	CG5024 / 43117	FlyBaseID:	FBgn0039373	Length:	165	Species:	Drosophila melanogaster
Sequence 2:	XP_011523141.2	Gene:	MYL4 / 4635	HGNCID:	7585	Length:	228	Species:	Homo sapiens

Alignment Length:	141	Identity:	41/141 - (29%)
Similarity:	67/141 - (47%)	Gaps:	13/141 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 AFALFDDDNAKVIPIKL--LRDCLRAVAHNPPENEIQDYITEIDTDGSGELYLSDF------LYI 88
            ||:|||......:.|..  ..|.|||:..||...|:...:.:...: ...:.:.||      |..
Human    90 AFSLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPE-EMNVKMLDFETFLPILQH 153

  Fly    89 MSKRYENLTVEDEVILAFKVFDKDGSGFIHENEFRQIMTEYGDEMEEDEIEEMIR-DADANTELK 152
            :|:..|..|.|| .:...:||||:.:|.:...|.|.::...|::|.|.|:|:::. ..|||.  .
Human   154 ISRNKEQGTYED-FVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQEDANG--C 215

  Fly   153 IDYVRFVTMMM 163
            |:|..||..:|
Human   216 INYEAFVKHIM 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5024	NP_001163736.1	PTZ00184	21..163	CDD:185504	40/139 (29%)
		EFh	28..90	CDD:298682	16/65 (25%)
		EFh	64..127	CDD:238008	16/68 (24%)
		EFh	101..163	CDD:298682	19/62 (31%)
MYL4	XP_011523141.2	EFh_PEF	86..227	CDD:330173	41/141 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010