DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5024 and MYL1

DIOPT Version :9

Sequence 1:	NP_001163736.1	Gene:	CG5024 / 43117	FlyBaseID:	FBgn0039373	Length:	165	Species:	Drosophila melanogaster
Sequence 2:	NP_524144.1	Gene:	MYL1 / 4632	HGNCID:	7582	Length:	194	Species:	Homo sapiens

Alignment Length:	146	Identity:	43/146 - (29%)
Similarity:	72/146 - (49%)	Gaps:	9/146 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EQLKDCEAAFALFDDDNAKVIPIKLLRDCLRAVAHNPPENEIQDYITEIDTD--GSGELYLSDFL 86
            ||..:.:.||.|||......|.:..:.|.|||:..||...|::..:.....:  .:.::....||
Human    50 EQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFL 114

  Fly    87 YIM---SKRYENLTVEDEVILAFKVFDKDGSGFIHENEFRQIMTEYGDEMEEDEIEE-MIRDADA 147
            .:|   |...:..|.|| .:...:||||:|:|.:...|.|.::...|::|:|:|:|. |....|:
Human   115 PMMQAISNNKDQATYED-FVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDS 178

  Fly   148 NTELKIDYVRFVTMMM 163
            |.  .|:|..||..:|
Human   179 NG--CINYEAFVKHIM 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5024	NP_001163736.1	PTZ00184	21..163	CDD:185504	42/144 (29%)
		EFh	28..90	CDD:298682	16/66 (24%)
		EFh	64..127	CDD:238008	16/67 (24%)
		EFh	101..163	CDD:298682	20/62 (32%)
MYL1	NP_524144.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35
		PTZ00184	45..193	CDD:185504	43/146 (29%)
		EFh	54..118	CDD:298682	15/63 (24%)
		EF-hand_6	54..83	CDD:290141	10/28 (36%)
		EFh	131..192	CDD:238008	21/63 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010