DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5024 and CALML6

DIOPT Version :9

Sequence 1:	NP_001163736.1	Gene:	CG5024 / 43117	FlyBaseID:	FBgn0039373	Length:	165	Species:	Drosophila melanogaster
Sequence 2:	XP_005244786.2	Gene:	CALML6 / 163688	HGNCID:	24193	Length:	203	Species:	Homo sapiens

Alignment Length:	152	Identity:	46/152 - (30%)
Similarity:	79/152 - (51%)	Gaps:	1/152 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 EVRTVHTHTLNDEQLKDCEAAFALFDDDNAKVIPIKLLRDCLRAVAHNPPENEIQDYITEIDTDG 76
            :..|..|..|:.||:|:.:..|.:||::....:....|...:..:..||.::|:.....::|.|.
Human    43 QTTTDMTERLSAEQIKEYKGVFEMFDEEGNGEVKTGELEWLMSLLGINPTKSELASMAKDVDRDN 107

  Fly    77 SGELYLSDFLYIMSKRYENL-TVEDEVILAFKVFDKDGSGFIHENEFRQIMTEYGDEMEEDEIEE 140
            .|......||.:|...:|.. ..|.|:..||:||||:|.|:|..|..:.::...|:.:.|.|.|:
Human   108 KGFFNCDGFLALMGVYHEKAQNQESELRAAFRVFDKEGKGYIDWNTLKYVLMNAGEPLNEVEAEQ 172

  Fly   141 MIRDADANTELKIDYVRFVTMM 162
            |:::||.:.:..|||..||.||
Human   173 MMKEADKDGDRTIDYEEFVAMM 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5024	NP_001163736.1	PTZ00184	21..163	CDD:185504	44/143 (31%)
		EFh	28..90	CDD:298682	12/61 (20%)
		EFh	64..127	CDD:238008	20/63 (32%)
		EFh	101..163	CDD:298682	25/62 (40%)
CALML6	XP_005244786.2	PTZ00184	48..195	CDD:185504	45/147 (31%)
		EFh	59..120	CDD:238008	12/60 (20%)
		EFh	133..195	CDD:238008	25/62 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1470794at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23050
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020