DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4956 and zdhhc15b

DIOPT Version :9

Sequence 1:	NP_651428.2	Gene:	CG4956 / 43114	FlyBaseID:	FBgn0039370	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001071249.1	Gene:	zdhhc15b / 777734	ZFINID:	ZDB-GENE-061110-106	Length:	332	Species:	Danio rerio

Alignment Length:	312	Identity:	65/312 - (20%)
Similarity:	114/312 - (36%)	Gaps:	113/312 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 FCAIFLLCLIGL---------LFVYELCYVLPQITDPHGIWHKLCWFMGIYTVINILGNWWLGCM 99
            :..:|.||.:.|         |.::.:|:::            .||            .:|....
Zfish    31 YAYVFELCFVTLSNNLGRVTYLLIFHVCFIM------------FCW------------TYWKAIF 71

  Fly   100 TNTSVDS-------------------------LV-LERQYPV--AGEAHLWHYCSTCQKLVPPRS 136
            |..|..:                         || :.::.|:  ..::....:|..||.:.|.|.
Zfish    72 TPPSTPTKKFHLSYTDKERYEMEERPEVQKQILVDIAKKLPIFTRAQSGAIRFCDRCQVIKPDRC 136

  Fly   137 WHCSLCNICILKRDHHCTFFASCIGHKNQRYFLAFLFHLSFGSGQALVYNGILNWTNKAFLVVDP 201
            .|||:|..|:||.||||.:..:|:|..|.::||.||.:       :::|...:..|      |..
Zfish   137 HHCSVCETCVLKMDHHCPWVNNCVGFSNYKFFLLFLSY-------SMIYCVFIAST------VFQ 188

  Fly   202 LLLMFQDTTQDADFKW---------KYTIANLFKLNLFLFGVPLFMFVFQMIMVYRNSTCYKML- 256
            ..|.|          |         |:.:..|..:.|..|...:|:|.:...:|.:|.:..:..
Zfish   189 YFLKF----------WVGDLPNGPAKFHVLFLLFVALMFFVSLMFLFGYHCWLVAKNRSTLEAFS 243

  Fly   257 --------DRS-YDVGWRRNFDMVLGK-RRFWIFFSPTISS-------PLPT 291
                    ||: ::||..:|...|.|: ::.|  |.|..:|       ||.|
Zfish   244 PPVFQNGPDRNGFNVGLNKNLRQVFGEHKKLW--FIPVFTSQGDGHYFPLRT 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	37/136 (27%)
zdhhc15b	NP_001071249.1	zf-DHHC	16..292	CDD:303066	63/309 (20%)
zdhhc15b	NP_001071249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..332
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810