DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4956 and Zdhhc4

DIOPT Version :9

Sequence 1:	NP_651428.2	Gene:	CG4956 / 43114	FlyBaseID:	FBgn0039370	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_082655.1	Gene:	Zdhhc4 / 72881	MGIID:	1920131	Length:	343	Species:	Mus musculus

Alignment Length:	243	Identity:	61/243 - (25%)
Similarity:	97/243 - (39%)	Gaps:	60/243 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FH-RH--FQLHRIKVMGLLHP--FCAIFLLCLIGLLFVYELCYVLPQITDPHGIWHKLCWFMGIY 85
            || ||  |.:..:.:.||::.  .|.:|..|       .||.:.||.:..|             |
Mouse    61 FHTRHPTFIVLHLLLQGLVYAEYTCEVFGYC-------RELEFSLPYLLLP-------------Y 105

  Fly    86 TVINI-LGNWWLGCMTNTSV-----DSLVL------ERQYPVAGEAHLWHYCSTCQKLVPPRSWH 138
            .:::: |..:.|.|..|...     :|.:|      :..:|....      |.||....|.||.|
Mouse   106 VLLSVNLVFFTLTCAANPGTITKANESFLLQVYKFDDVMFPKNSR------CPTCDLRKPARSKH 164

  Fly   139 CSLCNICILKRDHHCTFFASCIGHKNQRYFLAFLFHLSFGSGQALVYNGILNWTNKAFL-----V 198
            |.||:.|:.:.||||.:..:|||..|.||||.:|..|:..:       ..:.....|||     |
Mouse   165 CRLCDRCVHRFDHHCVWVNNCIGAWNTRYFLIYLLTLTASA-------ATIATVTAAFLLRLVTV 222

  Fly   199 VDPLLLMFQDTTQDADFKWKYTIANLFKLNLFLFGVPLFMFVFQMIMV 246
            .|    ::|:|..| |......:..:|.:.......|..:|:...::|
Mouse   223 SD----LYQETYLD-DVGHFQAVDTVFLIQHLFLAFPRIVFLLGFVIV 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	38/129 (29%)
Zdhhc4	NP_082655.1	DHHC	151..292	CDD:396215	38/127 (30%)
Zdhhc4	NP_082655.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9NPG8	340..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810