DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4956 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_651428.2	Gene:	CG4956 / 43114	FlyBaseID:	FBgn0039370	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001028745.1	Gene:	Zdhhc6 / 66980	MGIID:	1914230	Length:	413	Species:	Mus musculus

Alignment Length:	339	Identity:	79/339 - (23%)
Similarity:	112/339 - (33%)	Gaps:	130/339 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 MGLLHPFCAIF---------LLCLIG---LLFVYELCYVLPQITDPHGIWHKLCWFMGIYTV--- 87
            ||:   ||::.         .||..|   .|.|..:|..:..|       ..:.|:..::|.
Mouse     1 MGI---FCSVIKFENLQDLRRLCHWGPIIALGVIAICSTMAMI-------DSVLWYWPLHTTGGS 55

  Fly    88 IN--ILGNWWL-------------------GCMTNTSVDSLVLERQYPVAGEAHLWHYCSTCQKL 131
            :|  :|.||.:                   |.....|.||:.|:             ||..||..
Mouse    56 VNFIMLINWTVMILYNYFNAMFAGPGFVPRGWKPEKSQDSMYLQ-------------YCKVCQAY 107

  Fly   132 VPPRSWHCSLCNICILKRDHHCTFFASCIGHKNQRYFLAFLFHLSFGSGQALVYNGILNWTNKAF 196
            ..|||.||..||.|::|.||||.:..:|.||:|...|..||.....|.            |:.||
Mouse   108 KAPRSHHCRKCNRCVMKMDHHCPWINNCCGHQNHASFTLFLLLAPLGC------------THAAF 160

  Fly   197 LVVDPLLLMFQDTTQDADFKWKYTIANL-----------------FKLNLFLFGVPL-------F 237
            :.|   :.|:........|.|.....::                 |...||..|:.|       .
Mouse   161 IFV---MTMYTQLYNRLSFGWNTVKIDMSAARRDPPPIVPFGLAAFAATLFALGLALGTTIAVGM 222

  Fly   238 MFVFQMIMVYRNSTC--------------YKMLDR----SYDVG--WRRNFDMVLGKRRFWIFFS 282
            :|..|:.::.||.|.              |..||.    .||:|  | :||..|.
Mouse   223 LFFIQIKIILRNKTSIESWIEEKAKDRIQYYQLDEVFIFPYDMGSKW-KNFKQVF---------- 276

  Fly   283 PTISSPLPTDGTQW 296
             |.|.....||.:|
Mouse   277 -TWSGVPEGDGLEW 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	41/151 (27%)
Zdhhc6	NP_001028745.1	DHHC	95..241	CDD:366691	44/173 (25%)
		SH3_2	317..396	CDD:369452
		Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9H6R6	410..413
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810