DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4956 and ZDHHC13

DIOPT Version :9

Sequence 1:NP_651428.2 Gene:CG4956 / 43114 FlyBaseID:FBgn0039370 Length:302 Species:Drosophila melanogaster
Sequence 2:NP_061901.2 Gene:ZDHHC13 / 54503 HGNCID:18413 Length:622 Species:Homo sapiens


Alignment Length:282 Identity:51/282 - (18%)
Similarity:102/282 - (36%) Gaps:86/282 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 CAIFLLCLIGLLFVYELCYVLPQITD-------------------PHGI---------------- 74
            |.:|||.::.::.::.:.|:|...:|                   |..:                
Human   290 CELFLLLMLSVITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVYLPTAFLLS 354

  Fly    75 ---WHKLCWFM--------------GIYTVINILGNWWLGCMTN----------TSVDSLVLERQ 112
               |..:.||:              .|::::..|..::....|:          ..|:.:.|.. 
Human   355 SVFWIFMTWFILFFPDLAGAPFYFSFIFSIVAFLYFFYKTWATDPGFTKASEEEKKVNIITLAE- 418

  Fly   113 YPVAGEAHLWHYCSTCQKLVPPRSWHCSLCNICILKRDHHCTFFASCIGHKNQRYFLAFLFHLSF 177
               .|......:|::|....|.||.||.:||.|:.:.|.||.:...|||..|..|::.|||.||.
Human   419 ---TGSLDFRTFCTSCLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSM 480

  Fly   178 GSGQALVYNGILNWTNKAFLVVDPLLLMFQDTTQDADFKWKYTIANLFKLNLFLFGVPLFMFVFQ 242
            ..|. ::|...:..::..            .||...|..|.|       ||..:...|..:::..
Human   481 VCGW-IIYGSFIYLSSHC------------ATTFKEDGLWTY-------LNQIVACSPWVLYILM 525

  Fly   243 MIMVYRNSTCYKMLDRSYDVGW 264
            :...:.:.:.:.:|::.:.:.:
Human   526 LATFHFSWSTFLLLNQLFQIAF 547

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4956NP_651428.2 zf-DHHC 123..251 CDD:279823 33/127 (26%)
ZDHHC13NP_061901.2 ANK 1. /evidence=ECO:0000250|UniProtKB:Q8IUH5 43..78
ANK 79..192 CDD:238125
ANK repeat 81..112 CDD:293786
ANK 2. /evidence=ECO:0000255 81..110
ANK repeat 114..146 CDD:293786
ANK 3. /evidence=ECO:0000255 115..144
ANKYR <145..271 CDD:223738
ANK repeat 148..179 CDD:293786
ANK 4. /evidence=ECO:0000255 148..177
ANK repeat 181..247 CDD:293786
ANK 5. /evidence=ECO:0000255 181..211
ANK 6. /evidence=ECO:0000255 216..245
ANK 7. /evidence=ECO:0000255 249..277
zf-DHHC 423..559 CDD:307600 34/145 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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