DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4956 and Hip14

DIOPT Version :9

Sequence 1:	NP_651428.2	Gene:	CG4956 / 43114	FlyBaseID:	FBgn0039370	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	51/221 - (23%)
Similarity:	81/221 - (36%)	Gaps:	74/221 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 PFCAIFLLCLIGLLFVYELCYVL----------------PQITDPH-------------GIWHKL 78
            ||.|.:   |.|::|.....|::                ..:.|.|             ..|..:
  Fly   303 PFTAFY---LAGIVFTVNTLYIIKFFLLGCLYSIFHTIGKALFDEHLMALLPLSVYLATKAWFYV 364

  Fly    79 CWFMGI-----YT-----VINILGNW------WLGCMTNTSVDSLVLERQY-------------- 113
            .|.|.|     :|     :|:.|..|      |.|   :..:.....|:::
  Fly   365 TWLMYIDDAVSFTATVCFLISSLLLWVCFLKSWKG---DPGIIRPTREQRFKTIIELSERGGIGF 426

  Fly   114 -PVAGEAHLWHYCSTCQKLVPPRSWHCSLCNICILKRDHHCTFFASCIGHKNQRYFLAFLFHLSF 177
             |.:       :||.|....|.||.|||:|:.|:.:.||||.:..:|||.||..||:.||:.|..
  Fly   427 EPAS-------FCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLI 484

  Fly   178 GSGQALVYNGILNWTNKAFLVVDPLL 203
            .... ::|.|...:.|:..:..|..|
  Fly   485 MCAW-MLYGGSKYYVNQCNVRFDDFL 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	30/81 (37%)
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	31/92 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810