DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4956 and CG10344

DIOPT Version :9

Sequence 1:	NP_651428.2	Gene:	CG4956 / 43114	FlyBaseID:	FBgn0039370	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_611671.1	Gene:	CG10344 / 37565	FlyBaseID:	FBgn0034729	Length:	278	Species:	Drosophila melanogaster

Alignment Length:	267	Identity:	86/267 - (32%)
Similarity:	129/267 - (48%)	Gaps:	28/267 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 CAIFLLCLIGLLFVYELCYVLPQITDPHGIWHKLCWFMGIYTVINILGNWWLGCMTNTSVDSLVL 109
            |.:.:...:.::|::|:..|||...:|.|.:|...:.|.::.|.||.||.....|.:|||:   :
  Fly    17 CFLIIAVFLPVVFMFEIVVVLPAFHEPGGFFHTFTFLMAMFLVFNIKGNMIACMMIDTSVN---V 78

  Fly   110 ERQYPVAGEAHLWHYCSTCQKLVPPRSWHCSLCNICILKRDHHCTFFASCIGHKNQRYFLAFLFH 174
            ::..|.:.:.: |..|..||||.|||||||..|.:|||||||||.:...|||.:|.|:|:.|:|:
  Fly    79 KKVEPPSDQLN-WRECGECQKLAPPRSWHCKACKVCILKRDHHCIYTGCCIGLRNHRFFMGFIFY 142

  Fly   175 LSFGSGQALVYNGILNWTNKAFL---------VVDPLLLMFQDTTQDADFKWKYTIANLFKLNLF 230
            |..||..|||||.|..|.....:         :..|:|.:...:.      |.......:.||:.
  Fly   143 LFVGSVYALVYNSIYMWVIHGHIYSNWVTVLKLACPMLHLVTGSF------WTNMYLVFYSLNIL 201

  Fly   231 LFGVPLFMFVFQMIMVYRNSTCYKMLDRS------YDVGWRRNFDMVLGKRRFWIFFSPTISSPL 289
            .....:.:..:.:.:|.|...   ..||:      ||.|..:|...|.|.|....:.||.|.|.|
  Fly   202 ALAYGVLLLAYHVPIVLRGGV---SADRTKESKEKYDRGVYQNLRSVFGNRMHLAWLSPLIRSDL 263

  Fly   290 PTDGTQW 296
            |.||..|
  Fly   264 PEDGYHW 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	47/136 (35%)
CG10344	NP_611671.1	zf-DHHC	93..220	CDD:279823	46/132 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469545
Domainoid	1	1.000	74	1.000	Domainoid score	I9123
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4533
Isobase	1	0.950	-	0	Normalized mean entropy	S3153
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D423262at33208
OrthoFinder	1	1.000	-	-		FOG0002152
OrthoInspector	1	1.000	-	-		otm26486
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22883
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1251
	11	10.850