DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4956 and Zdhhc23

DIOPT Version :9

Sequence 1:	NP_651428.2	Gene:	CG4956 / 43114	FlyBaseID:	FBgn0039370	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001007461.1	Gene:	Zdhhc23 / 332175	MGIID:	2685625	Length:	425	Species:	Mus musculus

Alignment Length:	191	Identity:	48/191 - (25%)
Similarity:	81/191 - (42%)	Gaps:	46/191 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 YCSTCQKLVPPRSWHCSLCNICILKRDHHCTFFASCIGHKNQRYFLAFL--FHLSFGSGQALVYN 186
            :|:.||.:.|.|:|||.:|.||:.:.||||.:..||:|..|.:.|:..|  |.|:...|.:|..|
Mouse   250 WCAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFILALSIFLLTSVYGISLTLN 314

  Fly   187 GILNWTNKAFLVVDPLLL--MFQDTTQDADFKWKYTIANLFKLNLFLFGVPLFMFVFQMIMVYRN 249
            .|..         |..|.  :|......|::....:...::...:...|: .::|:.|:|.:..|
Mouse   315 TICR---------DRSLFTALFYCPGVYANYSSALSFTCVWYSVIITAGM-AYIFLIQLINISYN 369

  Fly   250 ST-----------------CYKMLDR-SYDVGWRRNFDMVLGKRRFWIFFSP----TISSP 288
            .|                 |..::|. .|:.|:.||          |:.||.    |:.:|
Mouse   370 VTEREVQQALRQKTGRRLLCGLIVDTGQYNRGFLRN----------WLQFSTLGTHTVHTP 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	36/130 (28%)
Zdhhc23	NP_001007461.1	DHHC	248..374	CDD:396215	37/133 (28%)
Zdhhc23	NP_001007461.1	Interaction with NOS1. /evidence=ECO:0000250	422..425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810