DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4956 and zdhhc6

DIOPT Version :9

Sequence 1:	NP_651428.2	Gene:	CG4956 / 43114	FlyBaseID:	FBgn0039370	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001191086.1	Gene:	zdhhc6 / 324468	ZFINID:	ZDB-GENE-030131-3189	Length:	412	Species:	Danio rerio

Alignment Length:	331	Identity:	79/331 - (23%)
Similarity:	111/331 - (33%)	Gaps:	120/331 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LHRIKVMGLLHPFCAIFLLCLIGLLFVYELCYVLPQITDPHGIWHKLCWFMGIYTV---IN--IL 91
            ||.:|  .|.| :..|..|.:||             :.....|...:.|:..:.|.   ||  :|
Zfish    13 LHEVK--RLFH-WGPIIALTVIG-------------VCSSMAILDSIIWYWPLDTTGGSINFIML 61

  Fly    92 GNWWLGCMTNTSVDSLVLERQYPV--AGEAHL---W-----------HYCSTCQKLVPPRSWHCS 140
            .||.:          |:|...:..  .|..::   |           .:|..||....|||.||.
Zfish    62 INWTV----------LILYNYFNAMFVGPGYIPLEWKPEKQQDIMYLQFCRLCQGYKAPRSHHCR 116

  Fly   141 LCNICILKRDHHCTFFASCIGHKNQRYFLAFLFHLSFGS-GQALVYNGILNWTNKAFLVVDPLLL 204
            .||.|::|.||||.:..:|.||.|..||.:||.....|. ..||::                ::.
Zfish   117 KCNRCVMKMDHHCPWINNCCGHLNHAYFTSFLLLAPLGCIHAALIF----------------IMT 165

  Fly   205 MFQDTTQDADFKWK------------------YTIANLFKLNLFLFGVPL-------FMFVFQMI 244
            |:........|.|.                  ::|| .|...||..|:.|       .:|..||.
Zfish   166 MYTQLYDRISFGWSSVKIDMSAARHIHHPIMPFSIA-AFAATLFALGLALGTTIAVGMLFFIQMK 229

  Fly   245 MVYRNSTCY------KMLDR------------SYDVGWR-RNFDMVLGKRRFWIFFSPTISSPLP 290
            ::.||.|..      |..||            .||:|.| .||..|.           |.|....
Zfish   230 VILRNRTSIEAWIEEKAKDRIQYYQTGEDFIFPYDLGSRWENFKQVF-----------TWSGAPM 283

  Fly   291 TDGTQW 296
            .||.:|
Zfish   284 GDGIEW 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	42/153 (27%)
zdhhc6	NP_001191086.1	DHHC	95..241	CDD:396215	43/162 (27%)
zdhhc6	NP_001191086.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9H6R6	409..412
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810