Protein Alignment CG4956 and ZDHHC24

DIOPT Version :9

• Sequence 1: NP_651428.2
• Gene: CG4956 / 43114
• FlyBaseID: FBgn0039370
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_997223.1
• Gene: ZDHHC24 / 254359
• HGNCID: 27387
• Length: 284
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 80/258 - (31%)
• Similarity: 118/258 - (45%)
• Gaps: 33/258 - (12%)

  Fly    53 IGLLFVYELCYVL-----PQITDPHGIWHKLCWFMGIYTVINILGNWWLGCMTNTSVDSLVLERQ 112
            :||    ||.|||     |....|  :...|...:..:.::|:|||..|...::.|:..::|..:
Human    29 VGL----ELAYVLVLGPGPPPLGP--LARALQLALAAFQLLNLLGNVGLFLRSDPSIRGVMLAGR 87

  Fly   113 YPVAGEAHLWHYCSTCQKLVPPRSWHCSLCNICILKRDHHCTFFASCIGHKNQRYFLAF------ 171
                |....|.||..||..|||||.|||.|.:|||:|||||.....|:|..|.|.||..
Human    88 ----GLGQGWAYCYQCQSQVPPRSGHCSACRVCILRRDHHCRLLGRCVGFGNYRPFLCLLLHAAG 148

  Fly   172 -LFHLSFGSGQALVYNGILNW---TNKAFLVVDPLLLMFQDTTQDADFKWKYTIANLFKLNLFLF 232
             |.|:|...|.||  :.:|..   .:.|.|::.|.|::.......|.|...: :.:.......|.
Human   149 VLLHVSVLLGPAL--SALLRAHTPLHMAALLLLPWLMLLTGRVSLAQFALAF-VTDTCVAGALLC 210

  Fly   233 GVPLFMFVFQMIMVYRNSTCYKML--DRSYDVGWRRNFDMVLGKRRFWIFFSPTISSPLPTDG 293
            |..|   :|..:::.|..|.::..  ..|||:|...|....||.|...::..|.::||||.||
Human   211 GAGL---LFHGMLLLRGQTTWEWARGQHSYDLGPCHNLQAALGPRWALVWLWPFLASPLPGDG 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	45/137 (33%)
ZDHHC24	NP_997223.1	zf-DHHC	95..234	CDD:279823	46/144 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9123
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I4820
Isobase	1	0.950	-	0	Normalized mean entropy	S3153
OMA	1	1.010	-	-		QHG47998
OrthoDB	1	1.010	-	-		D423262at33208
OrthoFinder	1	1.000	-	-		FOG0002152
OrthoInspector	1	1.000	-	-		otm40467
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17421
SonicParanoid	1	1.000	-	-		X1251
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.820