DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4956 and Zdhhc14

DIOPT Version :9

Sequence 1:	NP_651428.2	Gene:	CG4956 / 43114	FlyBaseID:	FBgn0039370	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_666185.3	Gene:	Zdhhc14 / 224454	MGIID:	2653229	Length:	489	Species:	Mus musculus

Alignment Length:	271	Identity:	65/271 - (23%)
Similarity:	100/271 - (36%)	Gaps:	101/271 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 FC----------AIFLLCLI------GLLFVYELCYVLPQITDPHGIWHKLCWFMGIYTVINILG 92
            ||          .:|.|.||      ||.|.::..|:..:||.            .|..|..||.
Mouse    50 FCNGRIMMARQTGVFYLTLILILVTSGLFFAFDCRYLAEKITP------------AIPVVGGILF 102

  Fly    93 NWWLGCMTNTSV------------DSLVLERQYPVA--------------------GEAHLWHYC 125
            .:.:|.:..||.            ::..||||..:|                    |:.....||
Mouse   103 FFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDIANGTSSGGYRPPPRTKEVVINGQTVKLKYC 167

  Fly   126 STCQKLVPPRSWHCSLCNICILKRDHHCTFFASCIGHKNQRYFLAFLFHLSFGSG--QALVYNGI 188
            .||:...|||:.|||||:.|:.:.||||.:..:|:|.:|.|:|..|:..|||.:.  .|.|...:
Mouse   168 FTCKIFRPPRASHCSLCDNCVEQFDHHCPWVGNCVGKRNYRFFYMFILSLSFLTVFIFAFVITHV 232

  Fly   189 LNWT-NKAFL---------VVDPLLLMF-------------------QDTTQDADFKWK------ 218
            ::.: .|.||         |::.::..|                   |.|.:|....|.
Mouse   233 IHRSQQKGFLDALKDSPASVLEAVICFFSVWSIIGLSGFHTYLISSNQTTNEDIKGSWSNKRGKE 297

  Fly   219 ----YTIANLF 225
                |:..|:|
Mouse   298 NYNPYSYGNIF 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	40/144 (28%)
Zdhhc14	NP_666185.3	zf-DHHC	164..289	CDD:307600	36/124 (29%)
Zdhhc14	NP_666185.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	434..454
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810