DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4956 and dhhc-13

DIOPT Version :9

Sequence 1:	NP_651428.2	Gene:	CG4956 / 43114	FlyBaseID:	FBgn0039370	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_500889.2	Gene:	dhhc-13 / 186797	WormBaseID:	WBGene00019257	Length:	593	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	48/208 - (23%)
Similarity:	76/208 - (36%)	Gaps:	54/208 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 FCAIFLLCLIGLLFVYELCYVLPQ--------------------------ITDPHGI--WHKLCW 80
            |...|.:.|.||.....|.::|.|                          |.:.:|:  |..|.:
Worm   298 FLTNFWVVLGGLALTALLLFILVQRRQMDQFGCLPVTYIFWMGIAEFALLIFNSNGLVHWSVLIF 362

  Fly    81 FMGIYTVINILGNWWLGCMTN--------TSVDSLVLERQYPVAGEAHLWHYCSTCQKLVPPRSW 137
            ...|:.:  ....:|:..:||        |.....:.:.:     |..:..||.||.......|.
Worm   363 VCSIWVI--SASFYWILILTNPGVLPRSTTPFKDFIKDLE-----EKQIDRYCFTCWIPKTSSSH 420

  Fly   138 HCSLCNICILKRDHHCTFFASCIGHKNQRYFL-----AFLFH------LSFGSGQALVYNGILNW 191
            |||.|:.|:...||||.:...|:..||.|.|:     .|:||      |.:..|.::..:|....
Worm   421 HCSQCDKCVDGFDHHCPWIHKCVYRKNLRAFVFFCLTIFMFHVFYVLLLLYMIGASMNASGFEQT 485

  Fly   192 TNKAFLVVDPLLL 204
            .|...|:|..|:|
Worm   486 LNDHGLMVISLIL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	30/93 (32%)
dhhc-13	NP_500889.2	ANK	42..155	CDD:238125
		Ank_2	42..132	CDD:289560
		ANK repeat	67..98	CDD:293786
		ANK repeat	101..132	CDD:293786
		Ank_5	121..176	CDD:290568
		ANK	130..>240	CDD:238125
		Ank_5	198..243	CDD:290568
		ANK repeat	206..234	CDD:293786
		zf-DHHC	405..530	CDD:279823	30/94 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810