DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17195 and ZDHHC18

DIOPT Version :9

Sequence 1:	NP_651427.2	Gene:	CG17195 / 43113	FlyBaseID:	FBgn0039369	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_115659.1	Gene:	ZDHHC18 / 84243	HGNCID:	20712	Length:	388	Species:	Homo sapiens

Alignment Length:	180	Identity:	56/180 - (31%)
Similarity:	84/180 - (46%)	Gaps:	25/180 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 VHPLSIVFVLCSTAFFFSLQMFYIAPKV---FGDIAYKLYWILV------TFITHNILGNMLAC- 77
            |..|:::.:|.:|..||.....|:|.|:   ...||..|::.::      :|....||.....|
Human    93 VFALTLLLILTTTGLFFVFDCPYLARKLTLAIPIIAAILFFFVMSCLLQTSFTDPGILPRATVCE 157

  Fly    78 --YMTSSSVNTLSKDSRCPNPEDEPLWH-------YCESCKKLRSPRSWHCVLCNTCILRRDHHC 133
              .:.....||.|...|.|....|.|.:       ||.:||..|.||:.||.:|:.|:.|.||||
Human   158 AAALEKQIDNTGSSTYRPPPRTREVLINGQMVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHC 222

  Fly   134 IFTGTCIGHNNQRFFFWFTFYLTLGLVTSFATFC----MFILQNGGNFMS 179
            .:.|.|:|..|.|||  :.|.|:|..:|:|...|    :.:...|.||:|
Human   223 PWVGNCVGRRNYRFF--YAFILSLSFLTAFIFACVVTHLTLRAQGSNFLS 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17195	NP_651427.2	zf-DHHC	103..234	CDD:279823	33/88 (38%)
ZDHHC18	NP_115659.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..67
		zf-DHHC	191..314	CDD:279823	33/82 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	364..388
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810