DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17195 and zdhhc4

DIOPT Version :9

Sequence 1:	NP_651427.2	Gene:	CG17195 / 43113	FlyBaseID:	FBgn0039369	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_956343.2	Gene:	zdhhc4 / 561817	ZFINID:	ZDB-GENE-030131-9031	Length:	345	Species:	Danio rerio

Alignment Length:	308	Identity:	68/308 - (22%)
Similarity:	109/308 - (35%)	Gaps:	95/308 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FVRIVHPL------SIVFVLCSTAF-----FFSLQMFYIAPKVFGDIAYKLYWILVTFITHNI-- 70
            |.|||.|.      ||.:......|     ||......:...|:|:..|:::...:...:.::
Zfish    39 FTRIVSPCIPQWLQSICYRTMHRLFHQRNNFFLYLHLLLEVVVYGEFTYEVFGFCLDMGSSSLSL 103

  Fly    71 --------LGNMLACYMTSSSVNTLSKDSRCPNPE----DEPLWHY---CESCKKLRSPRSWHCV 120
                    |.:.|.....|....||:|.:...:.:    ||.|:..   |.:|:.::..||.||.
Zfish   104 CVPYILLALKSCLFYLCCSRDPGTLTKSNLSAHLKIYQYDEKLFQQGMKCSTCQLIKPARSKHCR 168

  Fly   121 LCNTCILRRDHHCIFTGTCIGHNNQRFFFWFTFYLTLGLVTSFATFCMFILQNGGNFMSLSS-VI 184
            :||.|:.|.||||::...|||..|.|:|.   .||            :.:....||...|:: ::
Zfish   169 VCNRCVQRFDHHCVWVNNCIGAQNTRYFM---LYL------------LSVCAMAGNIAVLTTDML 218

  Fly   185 FNLITRT--------------------FFQNYTGNTFETIAFLLNISASYMPAFMLA------YQ 223
            ...:.||                    |...:...||..|.|:|.......  |:||      :.
Zfish   219 LQTVLRTGLLHAHYIDEQGIQQPAGPLFIIQHLFLTFPRIVFMLGFLVFVF--FLLAGYCLFHFY 281

  Fly   224 MQILSQNS-----------------------TYYNIFDCTYDLGFRKN 248
            :.:::|.|                       |.||.|...|..|..||
Zfish   282 LVLVNQTSNEWFKAKGHNCQHCHPYSGHNCRTSYNPFRGFYHRGILKN 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17195	NP_651427.2	zf-DHHC	103..234	CDD:279823	39/183 (21%)
zdhhc4	NP_956343.2	DHHC	152..296	CDD:396215	38/160 (24%)
zdhhc4	NP_956343.2	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9NPG8	342..345
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910