DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17195 and ZDHHC9

DIOPT Version :9

Sequence 1:	NP_651427.2	Gene:	CG17195 / 43113	FlyBaseID:	FBgn0039369	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001008223.1	Gene:	ZDHHC9 / 51114	HGNCID:	18475	Length:	364	Species:	Homo sapiens

Alignment Length:	262	Identity:	58/262 - (22%)
Similarity:	97/262 - (37%)	Gaps:	71/262 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LSIVFVLCSTAFFFSLQMFYIAPK------VFGDI--AYKLYWILVT-FITHNILGNML---ACY 78
            |::..:|.:...||:.:..|:|.:      ||..:  .:.:..:|.| |....::...|   |.:
Human    40 LTLFLILGTCTLFFAFECRYLAVQLSPAIPVFAAMLFLFSMATLLRTSFSDPGVIPRALPDEAAF 104

  Fly    79 --MTSSSVNTLSKDSRCPNPEDEPL--------WHYCESCKKLRSPRSWHCVLCNTCILRRDHHC 133
              |...:.|......:.|.|..:..        ..||.:||..|.||:.||.:|:.|:.|.||||
Human   105 IEMEIEATNGAVPQGQRPPPRIKNFQINNQIVKLKYCYTCKIFRPPRASHCSICDNCVERFDHHC 169

  Fly   134 IFTGTCIGHNNQRFFFWFTFYLTLGLVTSFATFCMFILQNGGNFMSLSSVIFNLITRTFFQNYTG 198
            .:.|.|:|..|.|:|:.|...|:|..:..||                    ||::       |..
Human   170 PWVGNCVGKRNYRYFYLFILSLSLLTIYVFA--------------------FNIV-------YVA 207

  Fly   199 NTFETIAFLLNISASYMPAFMLAYQMQILSQNSTYYNIFDCTYDLGFRKNCQTIMGQRGLWTFIS 263
            .....|.||..:..:                ..|...:..|.:.|      .:::|..|..||:.
Human   208 LKSLKIGFLETLKET----------------PGTVLEVLICFFTL------WSVVGLTGFHTFLV 250

  Fly   264 PL 265
            .|
Human   251 AL 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17195	NP_651427.2	zf-DHHC	103..234	CDD:279823	34/130 (26%)
ZDHHC9	NP_001008223.1	DHHC	138..261	CDD:396215	41/164 (25%)
ZDHHC9	NP_001008223.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..364
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810