DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17195 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_651427.2	Gene:	CG17195 / 43113	FlyBaseID:	FBgn0039369	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001032741.1	Gene:	Zdhhc6 / 361771	RGDID:	1304657	Length:	413	Species:	Rattus norvegicus

Alignment Length:	325	Identity:	70/325 - (21%)
Similarity:	118/325 - (36%)	Gaps:	94/325 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VNRFCHYFANRYPKNFVRIVHPLSI--VFVLCST-AFFFSLQMFYIAPKVFGDIAYKLYWILVTF 65
            :.|.||:             .|:..  |..:||| |...|:..::......|.:.:.:.......
  Rat    16 LRRLCHW-------------GPIIALGVIAICSTMAMIDSVLWYWPLHTTGGSVNFIMLINWTVM 67

  Fly    66 ITHNILGNMLACYMTSSSVNTLSKDSRCPNPEDEPLWHYCESCKKLRSPRSWHCVLCNTCILRRD 130
            |.:|....|.|      ....:.:..:..||:|.....||:.|:..::|||.||..||.|:::.|
  Rat    68 ILYNYFNAMFA------GPGFVPRGWKPENPQDSMYLQYCKVCQAYKAPRSHHCRKCNRCVMKMD 126

  Fly   131 HHCIFTGTCIGHNNQRFFFWFTFYLTLGLVTSFATFCMFILQNGGNFMSLSSVIFNLITRTFFQN 195
            |||.:...|.||.|...|..|.....||     .|...||.     .|::.:.::|.:      :
  Rat   127 HHCPWINNCCGHQNHASFTLFLLLAPLG-----CTHAAFIF-----VMTMYTQLYNRL------S 175

  Fly   196 YTGNT----------------------FETIAFLLNISASYMPAFMLAY--QMQILSQNST---- 232
            :..||                      |....|.|.::.....|..:.:  |::|:.:|.|
  Rat   176 FGWNTVKIDMSAARRDPPPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIKIILRNKTSIES 240

  Fly   233 -----------YY---NIFDCTYDLGFR-KNCQTIMGQRGLWTFISPLLKSPLPH-DGAHWQMKQ 281
                       ||   .:|...||:|.: ||.:.:.    .|        |.:|. ||..|.:::
  Rat   241 WIEEKAKDRIQYYQLDEVFVFPYDMGSKWKNLKQVF----TW--------SGVPEGDGLEWPIRE 293

Fly 282 281
Rat 294 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17195	NP_651427.2	zf-DHHC	103..234	CDD:279823	38/169 (22%)
Zdhhc6	NP_001032741.1	DHHC	95..241	CDD:396215	38/161 (24%)
Zdhhc6	NP_001032741.1	SH3_2	317..394	CDD:400139
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810