DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17195 and Zdhhc23

DIOPT Version :9

Sequence 1:	NP_651427.2	Gene:	CG17195 / 43113	FlyBaseID:	FBgn0039369	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001007461.1	Gene:	Zdhhc23 / 332175	MGIID:	2685625	Length:	425	Species:	Mus musculus

Alignment Length:	299	Identity:	63/299 - (21%)
Similarity:	105/299 - (35%)	Gaps:	110/299 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 TAFFFSLQMFYIAPKVFGDIAYKLYWIL-------------VTFITHNILGNMLACYMTSSSVNT 86
            |.||.||.:|        .:.|..|..|             :..:|..:|..:||.|....:...
Mouse   132 TLFFLSLGLF--------SLGYMYYVFLREVVPQGRVGPTQLALLTCGLLLILLALYRAKKNPGY 188

  Fly    87 LSKDS-------RCPNPE----------------------------------DEPL-----WHYC 105
            ||.|.       .||..:                                  |.|.     |  |
Mouse   189 LSNDKSPSNSQIECPVKKGQEKTKGFPGTDASGSLNNRTLKDDVRGSSRVGLDSPAKVKEDW--C 251

  Fly   106 ESCKKLRSPRSWHCVLCNTCILRRDHHCIFTGTCIGHNNQRFFFWFTFYLTLGLVTSFATFCMFI 170
            ..|:.:|..|:|||.:|..|:.|.||||::..:|:|.:|.:.|.   ..|::.|:||..
Mouse   252 AKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFI---LALSIFLLTSVY------ 307

  Fly   171 LQNGGNFMSLSSVI--FNLITRTF-----FQNYTGN-TFETIAFLLNISASYMPAFMLAYQMQIL 227
                |..::|:::.  .:|.|..|     :.||:.. :|..:.:.:.|:|..  |::...|:..:
Mouse   308 ----GISLTLNTICRDRSLFTALFYCPGVYANYSSALSFTCVWYSVIITAGM--AYIFLIQLINI 366

  Fly   228 SQNSTYYNIFDC------------------TYDLGFRKN 248
            |.|.|...:...                  .|:.||.:|
Mouse   367 SYNVTEREVQQALRQKTGRRLLCGLIVDTGQYNRGFLRN 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17195	NP_651427.2	zf-DHHC	103..234	CDD:279823	37/138 (27%)
Zdhhc23	NP_001007461.1	DHHC	248..374	CDD:396215	38/142 (27%)
Zdhhc23	NP_001007461.1	Interaction with NOS1. /evidence=ECO:0000250	422..425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810