DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17196 and Zdhhc17

DIOPT Version :9

Sequence 1:	NP_651426.1	Gene:	CG17196 / 43112	FlyBaseID:	FBgn0039368	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001034429.1	Gene:	Zdhhc17 / 366889	RGDID:	1595790	Length:	622	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	74/313 - (23%)
Similarity:	122/313 - (38%)	Gaps:	90/313 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KKAVSIGHPLSVIFL---------------------LVSTVFFFTLQVF------------YVAP 48
            ::.|.:|.|..||:|                     :.:||.|.:...|            |:|.
  Rat   292 RQKVMLGTPFLVIWLVGFIADLNIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLAT 356

  Fly    49 DVHDGFMYKFFV-ISAIFTTYN----------ILGNLLAC-YRTSSAVKSLP--------QER-- 91
                    ||:: ::..|..:|          .|.|.:|. |....:.||.|        |::
  Rat   357 --------KFWMYVTWFFWFWNDLSFLSIHLPFLANSVALFYNFGKSWKSDPGIIKATEEQKKKT 413

  Fly    92 --QIPKPGTEHLWHYCDICQKLMPPRSWHCALCKCCILKRDHHCIFAATCIGHNNHRYFFWLTFY 154
              ::.:.|:..|..:|..|....|.||.||.:|..||.|.||||.:...|:...|||||..   |
  Rat   414 IVELAETGSLDLSIFCSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVCAGNHRYFMG---Y 475

  Fly   155 LAFGIFMSMATLFVDVGRSFYLLH----RMKAGFGNTVKSL---SYFRYVCLILNIFALGFPALM 212
            |.|.:||....::..|  |::.||    ..|.||...:..:   |.:.:...:.::|...:.|::
  Rat   476 LFFLLFMICWMIYGCV--SYWGLHCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVL 538

  Fly   213 LRFQVQILKLNSTYYQISSRHHDLGFRNNCQLIMGQRGLWTFISPSLRSPLPH 265
            |..|:         |||:.    ||...|.::...:...:...:.|:.||..|
  Rat   539 LMCQM---------YQITC----LGITTNERMNARRYKHFKVTTTSIESPFNH 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17196	NP_651426.1	zf-DHHC	103..228	CDD:279823	38/131 (29%)
Zdhhc17	NP_001034429.1	Necessary and sufficient for interaction with DNAJC5 and SNAP25. /evidence=ECO:0000250\|UniProtKB:Q80TN5	1..295		0/2 (0%)
		Ank_4	<60..100	CDD:290365
		ANK	77..192	CDD:238125
		ANK repeat	79..110	CDD:293786
		Ank_2	84..177	CDD:289560
		ANK repeat	112..144	CDD:293786
		ANK	143..267	CDD:238125
		ANK repeat	146..177	CDD:293786
		Ank_2	151..245	CDD:289560
		ANK repeat	179..211	CDD:293786
		ANK repeat	214..245	CDD:293786
		zf-DHHC	428..558	CDD:279823	44/147 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810