DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17196 and zdhhc8b

DIOPT Version :9

Sequence 1:	NP_651426.1	Gene:	CG17196 / 43112	FlyBaseID:	FBgn0039368	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_840089.2	Gene:	zdhhc8b / 352941	ZFINID:	ZDB-GENE-030407-3	Length:	751	Species:	Danio rerio

Alignment Length:	270	Identity:	63/270 - (23%)
Similarity:	104/270 - (38%)	Gaps:	54/270 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PKKAVSIGHPLSVIFLLVSTVFFF-------TLQVFYVAPDVHDGFMYKFFVISAIFTTYNILGN 73
            |.|.:.:.  .:...|:.||..||       |..|..|.| :::|.::.|.:.:....|:...|.
Zfish    11 PTKYIPVS--TAATLLVGSTTLFFVFTCPWLTKAVSPVVP-LYNGIVFLFVLANFSMATFMDPGV 72

  Fly    74 LLAC---------YRTSSAVKSLPQERQIPKPGTEHLWHYCDICQKLMPPRSWHCALCKCCILKR 129
            ....         :|.       |..:.:...|.:....:|..|....|||..||::|..|:.:.
Zfish    73 FPRADEDEDKDDDFRA-------PLYKNVEIKGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEEF 130

  Fly   130 DHHCIFAATCIGHNNHRYFFWLTFYLAFGIFM----SMATLFVDVGRSFYLLHRMKAGFGNTVKS 190
            ||||.:...|||..|:||||  .|.|:..:.|    |...||        :||.::     |:.:
Zfish   131 DHHCPWVNNCIGRRNYRYFF--LFLLSLSVHMVGVFSFGLLF--------MLHHLE-----TLSA 180

  Fly   191 L--SYFRYVCLILNIFALGFPALMLRFQVQILKLNSTYYQISSRHHDLGFRNNCQLIMGQRGLWT 253
            |  :....|..:..:|.:....|.....|.:.:..:|..|::.:     ||......  .||...
Zfish   181 LHTTVTLVVMCVTGLFFIPVMGLTGFHMVLVARGRTTNEQVTGK-----FRGGVNPF--TRGCGG 238

  Fly   254 FISPSLRSPL 263
            .:...|.|||
Zfish   239 NVKHVLCSPL 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17196	NP_651426.1	zf-DHHC	103..228	CDD:279823	36/130 (28%)
zdhhc8b	NP_840089.2	zf-DHHC	99..224	CDD:279823	37/139 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..346
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	437..461
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	633..659
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	666..685
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	703..736
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810