DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17196 and ZDHHC20

DIOPT Version :9

Sequence 1:NP_651426.1 Gene:CG17196 / 43112 FlyBaseID:FBgn0039368 Length:276 Species:Drosophila melanogaster
Sequence 2:NP_001316988.1 Gene:ZDHHC20 / 253832 HGNCID:20749 Length:365 Species:Homo sapiens


Alignment Length:269 Identity:57/269 - (21%)
Similarity:102/269 - (37%) Gaps:52/269 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 LSVIFLLVSTVFFFTLQ--VFYVAPDVHDGFMYKFFVISAIFTTYNILGNLLACYRTSSA----- 83
            |.:.|::|.:.:.:.::  ||.:..:..:|....:.|...:|....:....:..: ||.|     
Human    20 LFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLVAFHLFFVMFVWSYWMTIF-TSPASPSKE 83

  Fly    84 -----------VKSLPQERQ------------IPKPGTEHLWHYCDICQKLMPPRSWHCALCKCC 125
                       .|...||||            |..........||:.||.:.|.|:.||:.|..|
Human    84 FYLSNSEKERYEKEFSQERQQEILRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSC 148

  Fly   126 ILKRDHHCIFAATCIGHNNHRYF-FWLTFYLAFGIFMSMATL----------FVDVGRSFYLLHR 179
            |||.||||.:...|:|.:|:::| .:|.:.|.:.:|::...|          ..|....|::|..
Human   149 ILKMDHHCPWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRAKFHVLFL 213

  Fly   180 MKAGFGNTVKSLSYFRYVCLILNIFALGFPALMLRFQVQILKLNSTYYQISSRHHDLGFRNNCQL 244
            ........:..||.|.|.|.::.         ..|..::..:..:..|........||...|.:.
Human   214 FFVSAMFFISVLSLFSYHCWLVG---------KNRTTIESFRAPTFSYGPDGNGFSLGCSKNWRQ 269

  Fly   245 IMG-QRGLW 252
            :.| ::..|
Human   270 VFGDEKKYW 278

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17196NP_651426.1 zf-DHHC 103..228 CDD:279823 34/135 (25%)
ZDHHC20NP_001316988.1 zf-DHHC 16..301 CDD:327686 57/269 (21%)
Substrate binding. /evidence=ECO:0000305|PubMed:29326245 140..143 1/2 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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