DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17196 and ZDHHC15

DIOPT Version :9

Sequence 1:	NP_651426.1	Gene:	CG17196 / 43112	FlyBaseID:	FBgn0039368	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_659406.1	Gene:	ZDHHC15 / 158866	HGNCID:	20342	Length:	337	Species:	Homo sapiens

Alignment Length:	312	Identity:	69/312 - (22%)
Similarity:	115/312 - (36%)	Gaps:	111/312 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 YANLYPKKAVSIGHPL-SVIFLLV---STVFF--------FTL-----QVFYVA----------- 47
            ||.::....|::..|. .||:|::   ..|||        |||     |.|:::
Human    37 YAYVFELCLVTVLSPAEKVIYLILYHAIFVFFTWTYWKSIFTLPQQPNQKFHLSYTDKERYENEE 101

  Fly    48 -PDVHDGFMYKFFVISAIFTTYNILGNLLACYRT-SSAVKSLPQERQIPKPGTEHLWHYCDICQK 110
             |:|....:........::|            || |.||:                  :||.|..
Human   102 RPEVQKQMLVDMAKKLPVYT------------RTGSGAVR------------------FCDRCHL 136

  Fly   111 LMPPRSWHCALCKCCILKRDHHCIFAATCIGHNNHRYFFWLTFYLAFGIFMSMATLFVDVGRSFY 175
            :.|.|..||::|..|:||.||||.:...|||.:|:::|..   :||:.:              .|
Human   137 IKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQ---FLAYSV--------------LY 184

  Fly   176 LLHRMKAGFGNTVKSLSYFR----------YVCLILNIFALGFPALMLRF--QVQILKLNSTYYQ 228
            .|:.....|...:|   |:|          :|..:|.:..:.|.:|::.|  ...::..|.|..:
Human   185 CLYIATTVFSYFIK---YWRGELPSVRSKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLE 246

  Fly   229 I----------SSRHHDLGFRNNCQLIMGQRGLWTFISPSLRSPL---PHDG 267
            .          .....:|||..|.|.:.|.:..:..|      |:   |.||
Human   247 AFCTPVFTSGPEKNGFNLGFIKNIQQVFGDKKKFWLI------PIGSSPGDG 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17196	NP_651426.1	zf-DHHC	103..228	CDD:279823	35/136 (26%)
ZDHHC15	NP_659406.1	zf-DHHC	<126..308	CDD:327686	48/211 (23%)
ZDHHC15	NP_659406.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..337
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810