DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17197 and AKR1

DIOPT Version :9

Sequence 1:	NP_651425.2	Gene:	CG17197 / 43111	FlyBaseID:	FBgn0039367	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_010550.1	Gene:	AKR1 / 851857	SGDID:	S000002672	Length:	764	Species:	Saccharomyces cerevisiae

Alignment Length:	295	Identity:	51/295 - (17%)
Similarity:	98/295 - (33%)	Gaps:	99/295 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 TTIFFVVLQMFYVVPQLFDVQGFMYKLGWLVAIFITYNIFGNML----ACHITSTSVESLPKDRQ 94
            |.::..::..|.|:|:.|..:.:...|..::.:.:.| :||.::    .|
Yeast   395 TLLWVTIVWFFKVMPRTFSDEQYTNILMLVILVSVFY-LFGQLVIMDPGC--------------- 443

  Fly    95 IPEPEEEHQ-----------------WHYCDVCEKLMPPRSWHCILCKCCILKRDRHCIFTASCV 142
            :|| |.:|:                 .::|.......|.||....|....:.:.|.:|.:..:.|
Yeast   444 LPE-ETDHENVRQTISNLLEIGKFDTKNFCIETWIRKPLRSKFSPLNNAVVARFDHYCPWIFNDV 507

  Fly   143 GHNNQRYFFWFTLFMALGTGVALATHIIATLKYFS-----------------------------Y 178
            |..|.:.|.:|...|..|    :.|.:...|:||.                             |
Yeast   508 GLKNHKAFIFFITLMESG----IFTFLALCLEYFDELEDAHEDTSQKNGKCFILGASDLCSGLIY 568

  Fly   179 SDLIFLNIPRDNLPPFWLVITLILNTYVFAAPVS----SVLMQ---------LSVLKNNGTLHKF 230
            ...:||.:....|...|:...:.:..:.....::    :|||:         ||..:|..|..:.
Yeast   569 DRFVFLILLWALLQSIWVASLIFVQAFQICKGMTNTEFNVLMKESKSIGPDGLSFNENFNTTPEG 633

  Fly   231 YSDTYDLGLWENFKLILGGKGFWTFLSPTVKSPLP 265
            ::.:.|.|...|               .||.:|:|
Yeast   634 FAPSIDPGEESN---------------DTVLAPVP 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17197	NP_651425.2	PHA02688	<9..70	CDD:222919	6/35 (17%)
CG17197	NP_651425.2	zf-DHHC	100..>198	CDD:279823	24/143 (17%)
AKR1	NP_010550.1	ANK repeat	75..101	CDD:293786
		ANKYR	78..270	CDD:223738
		ANK repeat	103..140	CDD:293786
		ANK repeat	142..173	CDD:293786
		ANK repeat	213..244	CDD:293786
		ANK repeat	246..271	CDD:293786
		COG5273	363..725	CDD:227598	51/295 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810