DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17197 and ZDHHC7

DIOPT Version :9

Sequence 1:	NP_651425.2	Gene:	CG17197 / 43111	FlyBaseID:	FBgn0039367	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001139020.1	Gene:	ZDHHC7 / 55625	HGNCID:	18459	Length:	345	Species:	Homo sapiens

Alignment Length:	206	Identity:	56/206 - (27%)
Similarity:	93/206 - (45%)	Gaps:	34/206 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 CHITSTSVESL-----PKDRQIPEPEEEHQW------HYCDVCEKLMPPRSWHCILCKCCILKRD 132
            |...:.||:||     ||.....|..|..|.      :.|..|..:.|.|:.||.:||.||.|.|
Human   130 CGEGTESVQSLLLGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMD 194

  Fly   133 RHCIFTASCVGHNNQRYFFWFTLFMALGTGVALATHIIATLKYFS-----YSDLIFLNIPRDNLP 192
            .||.:..:|||..|||:|..||:::||.:..||   |:...::.|     :::.      .|..|
Human   195 HHCPWVNNCVGEKNQRFFVLFTMYIALSSVHAL---ILCGFQFISCVRGQWTEC------SDFSP 250

  Fly   193 PFWLVITLILNT-----YVFAAPVSSVLMQLSVLKNNGTLHKFYSD--TYDLGL-WENFKLILGG 249
            |..:::.:.|..     :.|.|.:....:. |:..:...:.:..|:  |::..| ||..|.:.||
Human   251 PITVILLIFLCLEGLLFFTFTAVMFGTQIH-SICNDETEIERLKSEKPTWERRLRWEGMKSVFGG 314

  Fly   250 KGFWTFLSPTV 260
            .....:::|.|
Human   315 PPSLLWMNPFV 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17197	NP_651425.2	PHA02688	<9..70	CDD:222919
CG17197	NP_651425.2	zf-DHHC	100..>198	CDD:279823	34/108 (31%)
ZDHHC7	NP_001139020.1	zf-DHHC	168..295	CDD:307600	36/136 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810