DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17197 and ZDHHC13

DIOPT Version :9

Sequence 1:NP_651425.2 Gene:CG17197 / 43111 FlyBaseID:FBgn0039367 Length:290 Species:Drosophila melanogaster
Sequence 2:NP_061901.2 Gene:ZDHHC13 / 54503 HGNCID:18413 Length:622 Species:Homo sapiens


Alignment Length:280 Identity:64/280 - (22%)
Similarity:111/280 - (39%) Gaps:72/280 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 YLARRNPKIFVRISH----PTAVLFVIVTTIFFVVLQMFYVVPQLF--DVQGFMYKLGWLVAIFI 68
            :|....|:..|...:    |||.|   ::::|::.:..|.    ||  |:.|..:...::.:|..
Human   329 FLTSLFPRFLVGYKNLVYLPTAFL---LSSVFWIFMTWFI----LFFPDLAGAPFYFSFIFSIVA 386

  Fly    69 TYNIFGNMLACHITSTSVESLPKDRQIPEPEEEHQWH--------------YCDVCEKLMPPRSW 119
            ....|....|.....|...           |||.:.:              :|..|....|.||.
Human   387 FLYFFYKTWATDPGFTKAS-----------EEEKKVNIITLAETGSLDFRTFCTSCLIRKPLRSL 440

  Fly   120 HCILCKCCILKRDRHCIFTASCVGHNNQRYFFWFTLFMAL-------GTGVALATHIIATLK--- 174
            ||.:|.||:.:.|:||::|..|:|..|..|:.:|..|:::       |:.:.|::|...|.|   
Human   441 HCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDG 505

  Fly   175 YFSYSDLIFLNIPRDNLPPFWLVITLILNTYVFAAPVSSVLMQLSVLKNNG-TLHKFYS------ 232
            .::|.:.|....|       |::..|:|.|:.|:.....:|.||..:...| |.|:..|      
Human   506 LWTYLNQIVACSP-------WVLYILMLATFHFSWSTFLLLNQLFQIAFLGLTSHERISLQKQSK 563

  Fly   233 ----------DTYDLGLWEN 242
                      ..|:||..:|
Human   564 HMKQTLSLRKTPYNLGFMQN 583

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17197NP_651425.2 PHA02688 <9..70 CDD:222919 14/65 (22%)
zf-DHHC 100..>198 CDD:279823 31/121 (26%)
ZDHHC13NP_061901.2 ANK 1. /evidence=ECO:0000250|UniProtKB:Q8IUH5 43..78
ANK 79..192 CDD:238125
ANK repeat 81..112 CDD:293786
ANK 2. /evidence=ECO:0000255 81..110
ANK repeat 114..146 CDD:293786
ANK 3. /evidence=ECO:0000255 115..144
ANKYR <145..271 CDD:223738
ANK repeat 148..179 CDD:293786
ANK 4. /evidence=ECO:0000255 148..177
ANK repeat 181..247 CDD:293786
ANK 5. /evidence=ECO:0000255 181..211
ANK 6. /evidence=ECO:0000255 216..245
ANK 7. /evidence=ECO:0000255 249..277
zf-DHHC 423..559 CDD:307600 40/142 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S11709
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.760

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