DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17197 and Zdhhc23

DIOPT Version :9

Sequence 1:	NP_651425.2	Gene:	CG17197 / 43111	FlyBaseID:	FBgn0039367	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_001007461.1	Gene:	Zdhhc23 / 332175	MGIID:	2685625	Length:	425	Species:	Mus musculus

Alignment Length:	308	Identity:	58/308 - (18%)
Similarity:	109/308 - (35%)	Gaps:	115/308 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KIFVRISHPTAVL--------------FVIVTTIFFVVLQMFYVVPQ-----LFDVQGFMYKLGW 62
            |:.:.|..|..:|              .|::|::..:.|..:|:..:     ||.:...::.||:
Mouse    81 KVNISIVPPLVLLPVFLHVASWHFLLGVVVLTSLPMLALWYYYLTHRRKEQTLFFLSLGLFSLGY 145

  Fly    63 LVAIF-----------------ITYNIFGNMLACHITS-----TSVESLPKDRQIPEPEEEHQ-- 103
            :..:|                 :|..:...:||.:...     .|.:..|.:.||..|.::.|
Mouse   146 MYYVFLREVVPQGRVGPTQLALLTCGLLLILLALYRAKKNPGYLSNDKSPSNSQIECPVKKGQEK 210

  Fly   104 ---------------------------------------WHYCDVCEKLMPPRSWHCILCKCCIL 129
                                                   |  |..|:.:.|.|:|||.:|..|:.
Mouse   211 TKGFPGTDASGSLNNRTLKDDVRGSSRVGLDSPAKVKEDW--CAKCQLVRPARAWHCRICGICVR 273

  Fly   130 KRDRHCIFTASCVGH-NNQRYFFWFTLFMALGT-GVALATHIIATLK------------YFSYSD 180
            :.|.||::..||||. |:|.:....::|:.... |::|..:.|...:            |.:||.
Mouse   274 RMDHHCVWINSCVGESNHQAFILALSIFLLTSVYGISLTLNTICRDRSLFTALFYCPGVYANYSS 338

  Fly   181 LIFLNIPRDNLPPFW--LVITLILNTYVFAAPVSSVLMQLSVLKNNGT 226
            .:       :....|  ::||..: .|:|       |:||..:..|.|
Mouse   339 AL-------SFTCVWYSVIITAGM-AYIF-------LIQLINISYNVT 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17197	NP_651425.2	PHA02688	<9..70	CDD:222919	13/88 (15%)
CG17197	NP_651425.2	zf-DHHC	100..>198	CDD:279823	28/154 (18%)
Zdhhc23	NP_001007461.1	DHHC	248..374	CDD:396215	36/141 (26%)
Zdhhc23	NP_001007461.1	Interaction with NOS1. /evidence=ECO:0000250	422..425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810