DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17197 and ZDHHC24

DIOPT Version :9

Sequence 1:	NP_651425.2	Gene:	CG17197 / 43111	FlyBaseID:	FBgn0039367	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_997223.1	Gene:	ZDHHC24 / 254359	HGNCID:	27387	Length:	284	Species:	Homo sapiens

Alignment Length:	184	Identity:	57/184 - (30%)
Similarity:	81/184 - (44%)	Gaps:	25/184 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 WHYCDVCEKLMPPRSWHCILCKCCILKRDRHCIFTASCVGHNNQRYFFWFTLFMA---LGTGVAL 165
            |.||..|:..:||||.||..|:.|||:||.||.....|||..|.|.|....|..|   |...|.|
Human    93 WAYCYQCQSQVPPRSGHCSACRVCILRRDHHCRLLGRCVGFGNYRPFLCLLLHAAGVLLHVSVLL 157

  Fly   166 ATHIIATLKYFSYSDLIFLNIPRDNLPPFWLV------------ITLILNTYVFAAPV--SSVLM 216
            ...:.|.|:..:...:..|.:    ||  ||:            :..:.:|.|..|.:  :.:|.
Human   158 GPALSALLRAHTPLHMAALLL----LP--WLMLLTGRVSLAQFALAFVTDTCVAGALLCGAGLLF 216

  Fly   217 QLSVLKNNGTLHKFY--SDTYDLGLWENFKLILGGKGFWTFLSPTVKSPLPHDG 268
            ...:|....|..::.  ..:||||...|.:..||.:....:|.|.:.||||.||
Human   217 HGMLLLRGQTTWEWARGQHSYDLGPCHNLQAALGPRWALVWLWPFLASPLPGDG 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17197	NP_651425.2	PHA02688	<9..70	CDD:222919
CG17197	NP_651425.2	zf-DHHC	100..>198	CDD:279823	36/108 (33%)
ZDHHC24	NP_997223.1	zf-DHHC	95..234	CDD:279823	41/144 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9123
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I4820
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47998
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002152
OrthoInspector	1	1.000	-	-		otm40467
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1251
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.830