DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17197 and Zdhhc14

DIOPT Version :9

Sequence 1:	NP_651425.2	Gene:	CG17197 / 43111	FlyBaseID:	FBgn0039367	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_666185.3	Gene:	Zdhhc14 / 224454	MGIID:	2653229	Length:	489	Species:	Mus musculus

Alignment Length:	324	Identity:	68/324 - (20%)
Similarity:	118/324 - (36%)	Gaps:	106/324 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KYLARRNPKIF-----------VRISHPTAVLF-----VIVTTIFFVVLQMFY----VVPQLFDV 53
            |..|||..::|           :.::..|.|.:     ::||:..|......|    :.|.:..|
Mouse    33 KIAARRKWEVFPGRNKFFCNGRIMMARQTGVFYLTLILILVTSGLFFAFDCRYLAEKITPAIPVV 97

  Fly    54 QGFMYKLGWLVAIFITYNIFGNMLACHITSTSV-------ESLPKDRQI------------PEPE 99
            .|.::           :.:.|.:|....:...|       |:...:|||            |.|.
Mouse    98 GGILF-----------FFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDIANGTSSGGYRPPPR 151

  Fly   100 EEH--------QWHYCDVCEKLMPPRSWHCILCKCCILKRDRHCIFTASCVGHNNQRYFFWFTLF 156
            .:.        :..||..|:...|||:.||.||..|:.:.|.||.:..:|||..|.|:|:.|.|.
Mouse   152 TKEVVINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVEQFDHHCPWVGNCVGKRNYRFFYMFILS 216

  Fly   157 MALGTGVALA---THIIATLKYFSYSDLIFLNIPRDNLPPFWLVITLILNTYVFAAPVSSVLMQL 218
            ::..|....|   ||:|...:...:.|.:     :|:  |              |:.:.:|:...
Mouse   217 LSFLTVFIFAFVITHVIHRSQQKGFLDAL-----KDS--P--------------ASVLEAVICFF 260

  Fly   219 SVLKNNGTLHKFYSDTYDLGLWENFKLILGGKGFWTFLSPTVKSPLPHDGAQWKIKR-VQHHSP 281
            ||                   |.    |:|..||.|:|..:.::........|..|| .::::|
Mouse   261 SV-------------------WS----IIGLSGFHTYLISSNQTTNEDIKGSWSNKRGKENYNP 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17197	NP_651425.2	PHA02688	<9..70	CDD:222919	14/80 (18%)
CG17197	NP_651425.2	zf-DHHC	100..>198	CDD:279823	30/108 (28%)
Zdhhc14	NP_666185.3	zf-DHHC	164..289	CDD:307600	41/168 (24%)
Zdhhc14	NP_666185.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	434..454
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810