DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17197 and dhhc-13

DIOPT Version :9

Sequence 1:	NP_651425.2	Gene:	CG17197 / 43111	FlyBaseID:	FBgn0039367	Length:	290	Species:	Drosophila melanogaster
Sequence 2:	NP_500889.2	Gene:	dhhc-13 / 186797	WormBaseID:	WBGene00019257	Length:	593	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	56/213 - (26%)
Similarity:	90/213 - (42%)	Gaps:	47/213 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 TAVLFVI--------------VTTIFFVVLQMFYVVPQLFDVQGFMYKLGWLVAIF------ITY 70
            ||:|..|              ||.||::.:..|.::  :|:..|.::   |.|.||      |:.
Worm   312 TALLLFILVQRRQMDQFGCLPVTYIFWMGIAEFALL--IFNSNGLVH---WSVLIFVCSIWVISA 371

  Fly    71 NIFGNMLACHITSTSVESLPKDRQ-----IPEPEEEHQWHYCDVCEKLMPPRSWHCILCKCCILK 130
            :.:..::   :|:..|  ||:...     |.:.||:....||..|.......|.||..|..|:..
Worm   372 SFYWILI---LTNPGV--LPRSTTPFKDFIKDLEEKQIDRYCFTCWIPKTSSSHHCSQCDKCVDG 431

  Fly   131 RDRHCIFTASCVGHNNQRYFFWF--TLFMALGTGVALATHII-ATLKYFSYSDLIFLNIPRDNLP 192
            .|.||.:...||...|.|.|.:|  |:||.....|.|..::| |::....:...:     .|:
Worm   432 FDHHCPWIHKCVYRKNLRAFVFFCLTIFMFHVFYVLLLLYMIGASMNASGFEQTL-----NDH-- 489

  Fly   193 PFWLVITLILN-TYVFAA 209
             ..:||:|||. .:||.|
Worm   490 -GLMVISLILAIPHVFGA 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17197	NP_651425.2	PHA02688	<9..70	CDD:222919	16/63 (25%)
CG17197	NP_651425.2	zf-DHHC	100..>198	CDD:279823	26/100 (26%)
dhhc-13	NP_500889.2	ANK	42..155	CDD:238125
		Ank_2	42..132	CDD:289560
		ANK repeat	67..98	CDD:293786
		ANK repeat	101..132	CDD:293786
		Ank_5	121..176	CDD:290568
		ANK	130..>240	CDD:238125
		Ank_5	198..243	CDD:290568
		ANK repeat	206..234	CDD:293786
		zf-DHHC	405..530	CDD:279823	33/110 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810