DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17198 and AKR1

DIOPT Version :9

Sequence 1:	NP_001287532.1	Gene:	CG17198 / 43110	FlyBaseID:	FBgn0039366	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_010550.1	Gene:	AKR1 / 851857	SGDID:	S000002672	Length:	764	Species:	Saccharomyces cerevisiae

Alignment Length:	248	Identity:	48/248 - (19%)
Similarity:	92/248 - (37%)	Gaps:	77/248 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KSWTDIMGVSINVCIILFFYFFEAFYVMPQFLGLFGQAV------------HFLVTTWIVYNILE 85
            ::::|....:|.:.:||...|:           ||||.|            |            |
Yeast   410 RTFSDEQYTNILMLVILVSVFY-----------LFGQLVIMDPGCLPEETDH------------E 451

  Fly    86 NLRLCVTTLNTVDSLPPQMQQPMKGEEHLWHFCKICQRNVPPRSWHCNICDACILKRDHHCNFVG 150
            |:|..::.|..:            |:....:||.......|.||....:.:|.:.:.||:|.::.
Yeast   452 NVRQTISNLLEI------------GKFDTKNFCIETWIRKPLRSKFSPLNNAVVARFDHYCPWIF 504

  Fly   151 NCVGHNNQRYFIWF------SFYAAIGSAVALFDNFMLAH-----KHG----VGFFDLVKANYII 200
            |.||..|.:.||:|      ..:..:...:..||....||     |:|    :|..||...  :|
Yeast   505 NDVGLKNHKAFIFFITLMESGIFTFLALCLEYFDELEDAHEDTSQKNGKCFILGASDLCSG--LI 567

  Fly   201 FNAYMNPGRKELVIFYRIVSVLGVNIFAVLFPAALFCTQVVTVIKNSVMHDYS 253
            ::.::     .|::.:.::..:.|        |:|...|...:.|.....:::
Yeast   568 YDRFV-----FLILLWALLQSIWV--------ASLIFVQAFQICKGMTNTEFN 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17198	NP_001287532.1	zf-DHHC	43..>176	CDD:303066	31/150 (21%)
CG17198	NP_001287532.1	zf-DHHC	111..252	CDD:279823	32/155 (21%)
AKR1	NP_010550.1	ANK repeat	75..101	CDD:293786
		ANKYR	78..270	CDD:223738
		ANK repeat	103..140	CDD:293786
		ANK repeat	142..173	CDD:293786
		ANK repeat	213..244	CDD:293786
		ANK repeat	246..271	CDD:293786
		COG5273	363..725	CDD:227598	48/248 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900