DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17198 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_001287532.1	Gene:	CG17198 / 43110	FlyBaseID:	FBgn0039366	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001028745.1	Gene:	Zdhhc6 / 66980	MGIID:	1914230	Length:	413	Species:	Mus musculus

Alignment Length:	283	Identity:	64/283 - (22%)
Similarity:	112/283 - (39%)	Gaps:	52/283 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 GIMQSQVQMQTINIPRRVGAIKSWTDIMGVSINVCIILFFYFFEAFYVMPQFLGLFGQAVHFLV- 75
            ||..|.::.:.:...||   :..|..|:.:.:..............:..|  |...|.:|:|::
Mouse     2 GIFCSVIKFENLQDLRR---LCHWGPIIALGVIAICSTMAMIDSVLWYWP--LHTTGGSVNFIML 61

  Fly    76 ---TTWIVYNILENLRLCVTTLNTVDSLP---PQMQQPMKGEEHLW-HFCKICQRNVPPRSWHCN 133
               |..|:||.          .|.:.:.|   |:..:|.|.::.:: .:||:||....|||.||.
Mouse    62 INWTVMILYNY----------FNAMFAGPGFVPRGWKPEKSQDSMYLQYCKVCQAYKAPRSHHCR 116

  Fly   134 ICDACILKRDHHCNFVGNCVGHNNQRYFIWFSFYAAIGSAVALFDNFMLAHKHGVGFFDLVKANY 198
            .|:.|::|.||||.::.||.||.|...|..|...|.:|...|.|...|..:..   .::.:...:
Mouse   117 KCNRCVMKMDHHCPWINNCCGHQNHASFTLFLLLAPLGCTHAAFIFVMTMYTQ---LYNRLSFGW 178

  Fly   199 IIFNAYMNPGRKE--------LVIFYRIVSVLGVNIFAVLFPAALFCTQVVTVIKNS------VM 249
            ......|:..|::        |..|...:..||:.:...:....||..|:..:::|.      :.
Mouse   179 NTVKIDMSAARRDPPPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIKIILRNKTSIESWIE 243

  Fly   250 HDYSDR------------TYDLG 260
            ....||            .||:|
Mouse   244 EKAKDRIQYYQLDEVFIFPYDMG 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17198	NP_001287532.1	zf-DHHC	43..>176	CDD:303066	39/140 (28%)
CG17198	NP_001287532.1	zf-DHHC	111..252	CDD:279823	38/155 (25%)
Zdhhc6	NP_001028745.1	DHHC	95..241	CDD:366691	38/148 (26%)
		SH3_2	317..396	CDD:369452
		Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9H6R6	410..413
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810