DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17198 and Zdhhc23

DIOPT Version :9

Sequence 1:	NP_001287532.1	Gene:	CG17198 / 43110	FlyBaseID:	FBgn0039366	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001007461.1	Gene:	Zdhhc23 / 332175	MGIID:	2685625	Length:	425	Species:	Mus musculus

Alignment Length:	153	Identity:	40/153 - (26%)
Similarity:	68/153 - (44%)	Gaps:	33/153 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 MQQPMKGEEHLWHFCKICQRNVPPRSWHCNICDACILKRDHHCNFVGNCVGHNNQRYFIWFSFYA 168
            :..|.|.:|. |  |..||...|.|:|||.||..|:.:.||||.::.:|||.:|.:.||
Mouse   240 LDSPAKVKED-W--CAKCQLVRPARAWHCRICGICVRRMDHHCVWINSCVGESNHQAFI------ 295

  Fly   169 AIGSAVALFDNFMLAHKHGVGF-FDLVKANYIIFNA-YMNPG--------RKELVIFYRIVSVLG 223
                 :|| ..|:|...:|:.. .:.:..:..:|.| :..||        .....::|.::...|
Mouse   296 -----LAL-SIFLLTSVYGISLTLNTICRDRSLFTALFYCPGVYANYSSALSFTCVWYSVIITAG 354

  Fly   224 VNIFAVLFPAALFCTQVVTVIKN 246
            :        |.:|..|::.:..|
Mouse   355 M--------AYIFLIQLINISYN 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17198	NP_001287532.1	zf-DHHC	43..>176	CDD:303066	25/71 (35%)
CG17198	NP_001287532.1	zf-DHHC	111..252	CDD:279823	38/146 (26%)
Zdhhc23	NP_001007461.1	DHHC	248..374	CDD:396215	38/145 (26%)
Zdhhc23	NP_001007461.1	Interaction with NOS1. /evidence=ECO:0000250	422..425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810