DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17198 and ZDHHC8

DIOPT Version :9

Sequence 1:	NP_001287532.1	Gene:	CG17198 / 43110	FlyBaseID:	FBgn0039366	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001171953.1	Gene:	ZDHHC8 / 29801	HGNCID:	18474	Length:	778	Species:	Homo sapiens

Alignment Length:	156	Identity:	44/156 - (28%)
Similarity:	64/156 - (41%)	Gaps:	32/156 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 LFGQAVHFLVTT--WI---------VYN------ILENLRLCV-------TTLNTVDSLPPQMQQ 106
            |.|.:..|.|.|  |:         |||      :|.|..:..       ...:..:......:.
Human    24 LVGSSTLFFVFTCPWLTRAVSPAVPVYNGIIFLFVLANFSMATFMDPGVFPRADEDEDKEDDFRA 88

  Fly   107 PM------KGEEHLWHFCKICQRNVPPRSWHCNICDACILKRDHHCNFVGNCVGHNNQRYFIWF- 164
            |:      :|.:....:|..|....|||..||::||.|:...||||.:|.||:|..|.|||..|
Human    89 PLYKNVDVRGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFL 153

  Fly   165 -SFYAAIGSAVALFDNFMLAHKHGVG 189
             |..|.:...||....::|.|..|:|
Human   154 LSLSAHMVGVVAFGLVYVLNHAEGLG 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17198	NP_001287532.1	zf-DHHC	43..>176	CDD:303066	39/141 (28%)
CG17198	NP_001287532.1	zf-DHHC	111..252	CDD:279823	31/81 (38%)
ZDHHC8	NP_001171953.1	DHHC	99..224	CDD:366691	31/81 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..352
		PHA03247	<333..771	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	509..540
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810