Protein Alignment LpR2 and CD320

DIOPT Version :10

• Sequence 1: NP_001097928.1
• Gene: LpR2 / 43105
• FlyBaseID: FBgn0051092
• Length: 1064
• Species: Drosophila melanogaster
• Sequence 2: NP_057663.1
• Gene: CD320 / 51293
• HGNCID: 16692
• Length: 282
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 63/228 - (27%)
• Similarity: 88/228 - (38%)
• Gaps: 92/228 - (40%)

  Fly   274 SHTCSPEEFACKSGEGECIPLSWMCDQNKDCRDGSDEAQCNRTCRSDEFTCGNGRCIQNRFKCDD 338
            |.:|.|.:|.|:: .|.|:||:|.||::.||.|||||.:|.
Human    51 SGSCPPTKFQCRT-SGLCVPLTWRCDRDLDCSDGSDEEECR------------------------ 90

  Fly   339 DDDCGDGSDEKNCGEKAKCGSNFFACKSGPCIPNQWVCDGDSDCRNGED-EMQNCTVSLLNFCQA 402
                     .:.|.:|.:       |...|.:|  ..|.|.|||..|.| :::||:...   |.|
Human    91 ---------IEPCTQKGQ-------CPPPPGLP--CPCTGVSDCSGGTDKKLRNCSRLA---CLA 134

  Fly   403 GEFQCSDRITCLHKSWVCDGEADCPDGEDESQSNCLKVSCRPDQFQCNDQSCIAGHLTCNGKRDC 467
            ||.:|:....|:..:|.|||..||||..||                          |.|
Human   135 GELRCTLSDDCIPLTWRCDGHPDCPDSSDE--------------------------LGC------ 167

  Fly   468 ADGSDEIMCDISAT----PRTC-------NATT 489
              |::||:.:..||    |.|.       ||||
Human   168 --GTNEILPEGDATTMGPPVTLESVTSLRNATT 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LpR2	NP_001097928.1	LDLa	193..224	CDD:197566
		LDLa	235..267	CDD:197566
		LDLa	277..313	CDD:238060	18/35 (51%)
		LDLa	356..388	CDD:197566	10/32 (31%)
		LDLa	400..432	CDD:197566	14/31 (45%)
		LDLa	442..476	CDD:238060	5/33 (15%)
		LDLa	484..517	CDD:197566	5/13 (38%)
		FXa_inhibition	527..562	CDD:464251
		EGF_CA	564..594	CDD:214542
		LY	675..715	CDD:214531
		LY	717..760	CDD:214531
		LY	763..803	CDD:214531
		Ldl_recept_b	782..828	CDD:459654
		Ldl_recept_b	824..866	CDD:459654
		FXa_inhibition	877..918	CDD:464251
CD320	NP_057663.1	LDLa	54..89	CDD:238060	18/35 (51%)
		LDLa	132..167	CDD:238060	17/60 (28%)