Protein Alignment LpR2 and LOC100536757

DIOPT Version :10

• Sequence 1: NP_001097928.1
• Gene: LpR2 / 43105
• FlyBaseID: FBgn0051092
• Length: 1064
• Species: Drosophila melanogaster
• Sequence 2: XP_021334054.3
• Gene: LOC100536757 / 100536757
• -ID: -
• Length: 600
• Species: Danio rerio
• Alignment Length: 765
• Identity: 201/765 - (26%)
• Similarity: 311/765 - (40%)
• Gaps: 208/765 - (27%)

  Fly   291 CIPLSWMCDQNKDCRDGSDEAQCNRTCRSDEFTCGNGRCIQNRFKCDDDDDCGDGSDEKNCGEKA 355
            |:||:          :|..:      |...:|.|.|.||:....:||..:||||||||.:|
Zfish    28 CLPLT----------EGFPK------CTVLQFVCANSRCVSLSSRCDAVNDCGDGSDEISC---- 72

  Fly   356 KCGSNFFACKSGPCIPNQWVCDGDSDCRNGEDEMQNCTVSLLNFCQAGEFQCSDRITCLHKSWVC 420
                              |                |||        .|.|.|....:|:..|.||
Zfish    73 ------------------W----------------NCT--------NGSFHCVASESCVSSSSVC 95

  Fly   421 DGEADCPDGEDESQSNCLKVSCRPDQFQCNDQSCIAGHLTCNGKRDCADGSDEIMCDISATPRTC 485
            ||..||.||.||....|...|        ..|.|
Zfish    96 DGRPDCADGADEQLDTCTSFS--------QAQPC------------------------------- 121

  Fly   486 NATTEFDCGGGLCIPNAKVCNRRKDCPNGEDEPAGKCGINECSSKNGGCMHQCVNLEVGYRCECH 550
             |.:||.|..|.|:||:..|:...||.:|.||.  .|..|||:..||||.|.|::|..|:||:|.
Zfish   122 -ARSEFTCTNGQCVPNSWRCDHSSDCKDGSDEE--DCDHNECAVNNGGCSHTCIDLPFGFRCDCP 183

  Fly   551 DGYKLGADQHTCVDIDECETPGICSQVCVNEIGAFKCECEAGYMRLLKNHTRCKASEGHASLLLA 615
            .|.:|..|.| |..:|:|....:|.|:||:..|:..|:|:.|| :|.....:|:|:.|.|.:.::
Zfish   184 KGMRLVQDTH-CEVVDQCLDADVCDQICVHSNGSVVCDCQDGY-QLTAGTGQCRATGGLAHVAVS 246

  Fly   616 RRHDIRKIALDRPEMTSIVNSTKAATALDFVFRTGMIFWSDVATQSIYKAPIDEGNDRTVVLTKS 680
            .:..|:.:.|...|..:|.:...:...:..:.....::||......||:..:|.|:.|..|..|:
Zfish   247 TQEGIKMMDLSGSEERNITDKRLSPGPVSALNAHNTLYWSSPENDIIYRMSLDSGDHRPAVWLKA 311

  Fly   681 SVTSDGLAVDWIYNHVYFTDTHKCTIELTNFEGSMGKVLVKDSLDIPRSIALDPIEGWMYWSDWG 745
            |....|||||||:..:|:..|....:.:.:.:.:..::|: ..|..|.::|:.|:.|:::|::.|
Zfish   312 SKGIVGLAVDWIHESLYWISTSTRALHMASLKNTKQRLLI-SGLSKPTAVAVQPLLGYVFWAEGG 375

  Fly   746 ASPRIERAGMDGTHRTAIITYDVKWPNGITLDLVQKRLYWVDGKLNTISSSNYDGSQRHQVLYSG 810
            .|.||||.|:||..|.|::...|:.|..|:||:.:..|||.|..|.:||...:||..|..|:.|.
Zfish   376 ESARIERVGLDGESRFALVVSFVRNPVAISLDIPRGLLYWADSGLRSISRVLFDGQYRKTVVESN 440

  Fly   811 EYLRHPFSITTFEDYVYWTDWDKQAVFKANKFNGMDVEPVTATHMLEHPMVVHVYHPYRQPDGVN 875
            .||..||.:..||..|||:|....::..|:|.||.         ||..|.
Zfish   441 GYLDQPFGLAIFESRVYWSDQLTNSICSADKHNGT---------MLRVPQ--------------- 481

  Fly   876 HCQSVNGHCSHLCLPAPRINERSPRISCACPTGLKLMPDGLMCVEDLGIPTVRPTAPMHRTIEQS 940
                                    |:..|.|.||.::.           |.::|...:....|..
Zfish   482 ------------------------RLGSASPAGLVILH-----------PLLQPADKVLSPSEIK 511

  Fly   941 SNSTTKLPQDGYSETPVETKTGNNRTDTSNQVHKSDAESENDYVEIALHVIASLAGTALVASVIY 1005
            ::|..:|       .|.||||               |..::.:. :.|.:||.:....|...|::
Zfish   512 TSSNKEL-------LPSETKT---------------ALPDSQFT-LMLTLIAVILSVLLFGLVLW 553

  Fly  1006 VVYRR---CTRAVNSMNFENPVYHKTTED------------HFSLEKNGT 1040
              ::|   |  |..|::....|..|.::|            |.:|..|.|
Zfish   554 --WQRSELC--AHRSVSLLGDVTLKESQDPLLLSSLPAVHEHQTLSSNST 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LpR2	NP_001097928.1	LDLa	193..224	CDD:197566
		LDLa	235..267	CDD:197566
		LDLa	277..313	CDD:238060	4/21 (19%)
		LDLa	356..388	CDD:197566	1/31 (3%)
		LDLa	400..432	CDD:197566	13/31 (42%)
		LDLa	442..476	CDD:238060	2/33 (6%)
		LDLa	484..517	CDD:197566	12/32 (38%)
		FXa_inhibition	527..562	CDD:464251	16/34 (47%)
		EGF_CA	564..594	CDD:214542	10/29 (34%)
		LY	675..715	CDD:214531	12/39 (31%)
		LY	717..760	CDD:214531	16/42 (38%)
		LY	763..803	CDD:214531	14/39 (36%)
		Ldl_recept_b	782..828	CDD:459654	19/45 (42%)
		Ldl_recept_b	824..866	CDD:459654	11/41 (27%)
		FXa_inhibition	877..918	CDD:464251	5/40 (13%)
LOC100536757	XP_021334054.3	None