DRSC/TRiP Functional Genomics Resources

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Protein Alignment LpR2 and lrp5

DIOPT Version :9

Sequence 1:NP_001097928.1 Gene:LpR2 / 43105 FlyBaseID:FBgn0051092 Length:1064 Species:Drosophila melanogaster
Sequence 2:XP_002941689.1 Gene:lrp5 / 100491803 XenbaseID:XB-GENE-485117 Length:1603 Species:Xenopus tropicalis


Alignment Length:319 Identity:134/319 - (42%)
Similarity:191/319 - (59%) Gaps:11/319 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly   603 CKASE-GHASLLLARRHDIRKIALDRPEMTS--IVNSTKAATALDFVFRTGMIFWSDVATQSIYK 664
            |.||. |...||.|.|.|:|.:.....::.|  :|:..:.|.|:||::..|:|:|:||:.:||.:
 Frog    14 CLASSWGSPLLLFANRRDVRLVDAGGTKLESVVVVSGLEDAAAVDFLYSQGVIYWTDVSEESIKQ 78

  Fly   665 APIDEGNDRTVVLTKSSVTSDGLAVDWIYNHVYFTDTHKCTIELTNFEGSMGKVLVKDSLDIPRS 729
            ...::.::...|:....|:.||||.|||...:|:||:....||:.|..|:..|||....||.||:
 Frog    79 TLYNQSSNLQTVVISGLVSPDGLACDWIGKKLYWTDSETNRIEVGNLNGTYRKVLFWQDLDQPRA 143

  Fly   730 IALDPIEGWMYWSDWGASPRIERAGMDGTHRTAIITYDVKWPNGITLDLVQKRLYWVDGKLNTIS 794
            |||||..|:|||:|||.:||||||||||:.|..|:..|:.||||:|:||.:::|||.|.||:.|.
 Frog   144 IALDPAHGYMYWTDWGDTPRIERAGMDGSMRKVIVDTDIYWPNGLTIDLDEQKLYWADAKLSFIH 208

  Fly   795 SSNYDGSQRHQVLYSGEYLRHPFSITTFEDYVYWTDWDKQAVFKANKFNGMDVEPVTATHMLEHP 859
            .:|.|||.|.:|:...  |.|||::|...|.:|||||..:::...||..|.....:.::  |..|
 Frog   209 RANLDGSFRQKVVEGS--LTHPFALTLAGDTLYWTDWQTRSIHACNKRTGEKRREILSS--LYSP 269

  Fly   860 MVVHVYHPYRQPDGVNHCQSVNGHCSHLCLPAPRINERSPRISCACPTGLKLMPDGLMC 918
            |.:.|:...|||.....|...||.||||||.:|    |.|..||.||||::|..||..|
 Frog   270 MDIQVFSKERQPYFPTPCDESNGGCSHLCLLSP----REPFYSCTCPTGVQLTQDGKTC 324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LpR2NP_001097928.1 LDLa 193..224 CDD:197566
LDLa 235..267 CDD:197566
LDLa 277..313 CDD:238060
LDLa 356..388 CDD:197566
LDLa 400..432 CDD:197566
LDLa 442..476 CDD:238060
LDLa 484..517 CDD:197566
FXa_inhibition 527..562 CDD:291342
EGF_CA 564..594 CDD:214542
LY 675..715 CDD:214531 16/39 (41%)
LY 717..760 CDD:214531 29/42 (69%)
LY 763..803 CDD:214531 20/39 (51%)
FXa_inhibition 877..918 CDD:291342 21/40 (53%)
lrp5XP_002941689.1 LY 88..130 CDD:214531 16/41 (39%)
LY 131..174 CDD:214531 29/42 (69%)
LY 175..217 CDD:214531 20/41 (49%)
LY 218..252 CDD:214531 12/35 (34%)
FXa_inhibition 287..324 CDD:373209 21/40 (53%)
LY 354..394 CDD:214531
LY 396..438 CDD:214531
LY 439..482 CDD:214531
LY 484..525 CDD:214531
LY 526..559 CDD:214531
FXa_inhibition 593..628 CDD:373209
LY 657..697 CDD:214531
LY 698..740 CDD:214531
LY 741..783 CDD:214531
LY 785..826 CDD:214531
LY 826..867 CDD:214531
FXa_inhibition 894..929 CDD:373209
LY 958..998 CDD:214531
LY 1050..1093 CDD:214531
LY 1094..1136 CDD:214531
FXa_inhibition 1207..1243 CDD:373209
LDLa 1249..1285 CDD:238060
LDLa 1288..1322 CDD:238060
LDLa 1326..1360 CDD:238060
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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