Protein Alignment CG5028 and IDH1

DIOPT Version :9

• Sequence 1: NP_001097922.1
• Gene: CG5028 / 43102
• FlyBaseID: FBgn0039358
• Length: 402
• Species: Drosophila melanogaster
• Sequence 2: NP_014361.1
• Gene: IDH1 / 855691
• SGDID: S000004982
• Length: 360
• Species: Saccharomyces cerevisiae
• Alignment Length: 364
• Identity: 168/364 - (46%)
• Similarity: 238/364 - (65%)
• Gaps: 12/364 - (3%)

  Fly    25 VTKEKTEDVAHTKSALQKKVTGTDIPSAQYGGRHAVTMLPGGGIGPELMGYVREIFRYCGAPIDF 89
            :.|......|..:..|.||          ||||..||::||.|:|.|:...||.||.....|||:
Yeast     6 IAKRTLATAAQAERTLPKK----------YGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDW 60

  Fly    90 EVIDIDPSTEGNDDLDYAITSIKRNGVALKGNIETKSQSLTEVSRNVAIRNELDLYVNVVHCKSY 154
            |.|:| ..|:..:.:..|:.|:|||.:.|||...|.:......|.|||:|.:||:|.||...||.
Yeast    61 ETINI-KQTDHKEGVYEAVESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSL 124

  Fly   155 PGIPARHHDIDVVLIRQNTDGEYAMLEHESVPGIVESMKVVTVENAERVARYAFEFARQNNRKKV 219
            .|:..|..|||:::||:||:||::.||||||||:|||:||:|....||:||:||:||::.|||.|
Yeast   125 KGVKTRIPDIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSV 189

  Fly   220 TTIHKANIMKLSDGLFLEVANRV-HKDYPELEHNNMIIDNTCMQSVSNPHQFDVMNMTNLYGTIV 283
            |.:||||||||.||||..:...: .|:||:::.:::|:||..||:|:.||||||:...::||||:
Yeast   190 TAVHKANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTIL 254

  Fly   284 SNVLCGLMGGAGLISGRNYGDHYAIFEPGTRNTGTAIAGKNIANPVAMISASIDMLNHLGHKEHA 348
            .|:...|:||.||::|.|:|..||:||||:|:.|..|.|:|:|||.|||.:|..||||||..|:|
Yeast   255 GNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGLNEYA 319

  Fly   349 NVIQEAVYQTIVNDAIRTPDIGGTNSSTDVVENILKILS 387
            ..|.:||::||......|.||||::|:||....|:..||
Yeast   320 TRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLS 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5028	NP_001097922.1	mito_nad_idh	55..386	CDD:272942	160/331 (48%)
IDH1	NP_014361.1	mito_nad_idh	26..357	CDD:272942	160/331 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346415
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	327	1.000	Inparanoid score	I436
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53770
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	1	1.000	-	-		oto99609
orthoMCL	1	0.900	-	-		OOG6_101342
Panther	1	1.100	-	-	O	PTHR11835
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R585
SonicParanoid	1	1.000	-	-		X402
TreeFam	1	0.960	-	-
	12	11.790